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Takeda Termination and Transition Agreement (Narrative) (Details) (USD $)
12 Months Ended
Dec. 31, 2014
Dec. 31, 2013
Dec. 31, 2012
Takeda Termination And Transition Agreement Narrative Details      
Shares of Common Stock issued 0us-gaap_StockholdersEquityOtherShares 6.1us-gaap_StockholdersEquityOtherShares 0us-gaap_StockholdersEquityOtherShares
Value of Common Stock issued   $ 54,900,000us-gaap_StockholdersEquityOther  
Future milestone payment in cash or common stock   30,000,000npsp_FutureMilestonePaymentInCashOrCommonStock  
Milestone payment trigger amount on worldwide net sales   750,000,000npsp_MilestonePaymentTriggerAmountOnWorldwideNetSales  
Assets acquired:      
Revestive raw materials   16,600,000npsp_RevestiveRawMaterials  
PTH raw materials   17,100,000npsp_PthRawMaterials  
Revestive product rights   20,700,000us-gaap_FiniteLivedContractualRightsGross  
Estimated useful life of agreement   12 years  
Revestive products rights amortization expense 1,800,000npsp_RevestiveProductsRightsAmortizationExpense 1,400,000npsp_RevestiveProductsRightsAmortizationExpense  
Estimated annual amortization for each of the next five years $ 1,800,000npsp_EstimatedAnnualAmortizationForEachOfNextFiveYears