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Collaborative and License Agreements ( Narrative) (Details) (USD $)
In Millions, unless otherwise specified
12 Months Ended
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2011
Amgen Inc.
     
Year of agreement 1996    
Number of days to terminate upon written notice to the Company 90    
Percentage of Company costs to develop product 0.00%    
Nonrefundable license fee received $ 10.0    
Total milestone payments under the agreement payable to the Company 26.0    
Future milestone payments outside the Company's control 5.0    
Next future milestone payment outside the Company's control 5.0    
Total milestone payments paid to the Company to date 21.0    
Milestone payments received by the Company 0 0 0
Recognized royalties from product sales received by the Company 112.9 89.3 77.6
Sale of royalty rights 0 25.0 0
GlaxoSmithKline
     
Year of agreement 2011    
Total milestone payments under the agreement payable to the Company 11.5    
Future milestone payments outside the Company's control 1.0    
Total milestone payments paid to the Company to date 0    
Kyowa Hakko Kirin
     
Year of agreement 1995    
Number of days to terminate upon written notice to the Company 90    
Percentage of Company costs to develop product 0.00%    
Nonrefundable license fee received 5.0    
Total milestone payments under the agreement payable to the Company 13.0    
Research support payments under the agreement 7.0    
Total milestone payments paid to the Company to date 13.0    
Research support payments paid to the Company to date 7.0    
Milestone payments received by the Company 0 0 0
Recognized royalties from product sales received by the Company 8.0 8.7 7.6
Takeda Teduglutide
     
Year of agreement 2007    
Number of days to terminate upon written notice to the Company 180 or 365    
Percentage of Company costs to develop product 50.00%    
Nonrefundable license fee received 35.0    
Total milestone payments under the agreement payable to the Company 170.0    
Total milestone payments payable upon the achievement of certain pre-specified product development milestones 150.0    
Total milestone payments payable upon the achievement of certain pre-specified sales-based milestones 20.0    
Company payments to licensor to date 6.6    
Future milestone payments outside the Company's control 5.0    
Total milestone payments paid to the Company to date 40.0    
Milestone payments received by the Company 0 0 5.0
Company payments to licensor     2.4
Takeda Preotact
     
Year of agreement 2004 and 2007    
Number of days to terminate upon written notice to the Company 180    
Total milestone payments under the agreement payable to the Company 22.0    
Total milestone payments payable upon the achievement of certain pre-specified product development milestones 0.3    
Total milestone payments payable upon the achievement of certain pre-specified sales-based milestones 14.5    
Future milestone payments outside the Company's control 14.8    
Next future milestone payment outside the Company's control 0.3    
Total milestone payments paid to the Company to date 7.1    
Recognized royalties from product sales received by the Company 0 4.8 9.1
Janssen Pharmaceuticals, Inc.
     
Year of agreement 2006    
Number of days to terminate upon written notice to the Company 60    
Percentage of Company costs to develop product 0.00%    
Nonrefundable license fee received 8.0    
Recognized royalties from product sales received by the Company 2.9 2.8 2.2
Hoffman-La Roche Inc. and F. Hoffmann-La Roche Ltd.
     
Year of agreement 2008    
Number of days to terminate upon written notice to the Company 30    
Percentage of Company costs to develop product 0.00%    
Nonrefundable license fee received 2.0    
Total milestone payments paid to the Company to date 0.3    
Milestone payments received by the Company 0 0 0.3
Recognized royalties from product sales received by the Company 0 0 0
In-License and Purchase Agreements
     
Company maximum royalties to be paid on sales of cinacalcet HCl 15.0    
Royalties payable accrued on sales of cinacalcet HCl, to date 15.0    
Royalties paid on sales of cinacalcet HCl, to date 9.4    
Annual upper limit of royalty payments on sales of cinacalcet HCl 1.0    
Royalties recorded in other liabilites on sales of cinacalcet HCl 4.6    
Royalties recorded in accrued expenses and other liabilites on sales of cinacalcet HCl $ 1.0