Condensed Consolidated Statements of Operations (USD $) In Thousands, except Per Share data, unless otherwise specified	12 Months Ended
	Dec. 31, 2013	Dec. 31, 2012	Dec. 31, 2011
Revenues:
Product sales, net	$ 31,752	$ 0	$ 99
Royalties	123,804	105,587	96,502
Sale of royalty rights	0	25,000	0
Other	36	57	5,044
Total revenues	155,592	130,644	101,645
Operating expenses:
Cost of sales	3,587	0	0
Cost of royalties	0	0	500
Cost of license fees	9	0	2,543
Research and development	85,421	94,839	73,831
Selling, general and administrative	68,070	36,929	24,226
Total operating expenses	153,491	131,768	98,057
Operating (loss) income	(1,495)	(1,124)	545
Other income (expense)
Interest income, net	340	292	321
Interest expense	(11,938)	(18,198)	(37,736)
Gain on sale of marketable investment securities, net	4	4	0
Foreign currency transaction (loss) gain	(233)	54	318
Other	0	237	303
Total other expense, net	(11,827)	(17,611)	(36,794)
Loss before income tax expense	(13,322)	(18,735)	(36,249)
Income tax expense	182	0	18
Net loss	$ (13,504)	$ (18,735)	$ (36,267)
Net loss per common and potential common share
Basic	$ (0.14)	$ (0.22)	$ (0.45)
Diluted	$ (0.14)	$ (0.22)	$ (0.45)
Weighted average common and potential common shares outstanding
Basic	97,750	86,999	81,279
Diluted	97,750	86,999	81,279