Exhibit 99.2

August 3, 2005

Grace Brothers Ltd.

1560 Sherman Avenue, Suite 900

Evanston, Illinois 60201

Gentlemen:

Reference is made to your sales (including those sales of your affiliates) of ISCO International, Inc.’s (the “Company”) common stock over the past six (6) months. According to Company records, Grace Brothers (including its affiliates) currently owns, and has owned during the past six (6) months, at least 10% of the Company’s outstanding common stock and thus are subject to the reporting and other requirements of Section 16 of the Securities Exchange Act of 1934, as amended (the “Act”). As a result of the closing on August 2, 2005 of the financing (the “Financing”) in which Grace Brothers purchased 10,000,000 shares of the Company’s common stock pursuant to the Securities Purchase Agreement by and among the Company, Elliott Associates, L.P., Elliott International, L.P., and Grace Brothers Ltd dated July 25, 2005, the Company believes that the foregoing transactions are “matchable transactions” against all sales of common stock, by Grace Brothers or its affiliates, within six months of the purchase of shares in the Financing for the purpose of determining short-swing profit liability under Section 16(b) of the Act. The Company believes that the sale of 2,016,800 shares during the past six months qualify for review against the $0.22 purchase price in the August 2, 2005 purchase transaction.

By this letter, the Company hereby demands the prompt payment to the Company of the short-swing profit amount, by wire transfer of immediately available funds. Please advise if you have any questions in this matter.

Best Regards,

/s/ Frank Cesario

Frank J. Cesario

Chief Financial Officer

ISCO International

847-391-9412

fax: 847-391-5015 and 847-299-9609

cesario@iscointl.com

cc: Michael P. Gallagher, Esq.

Evelyn C. Arkebauer, Esq.