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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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 n1lnSA581IrTzo2R6LB+DA==

<SEC-DOCUMENT>0001192482-08-000024.txt : 20080111
<SEC-HEADER>0001192482-08-000024.hdr.sgml : 20080111
<ACCEPTANCE-DATETIME>20080111163732
ACCESSION NUMBER:		0001192482-08-000024
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20071231
FILED AS OF DATE:		20080111
DATE AS OF CHANGE:		20080111

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ISCO INTERNATIONAL INC
		CENTRAL INDEX KEY:			0000888693
		STANDARD INDUSTRIAL CLASSIFICATION:	INSTRUMENTS FOR MEAS & TESTING OF ELECTRICITY & ELEC SIGNALS [3825]
		IRS NUMBER:				363688459
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		1001 CAMBRIDGE DRIVE
		CITY:			ELK GROVE VILLAGE
		STATE:			IL
		ZIP:			60007
		BUSINESS PHONE:		8473919400

	MAIL ADDRESS:	
		STREET 1:		1001 CAMBRIDGE DRIVE
		CITY:			ELK GROVE VILLAGE
		STATE:			IL
		ZIP:			60007

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Thode John
		CENTRAL INDEX KEY:			0001315197

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-22302
		FILM NUMBER:		08526605

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		(847)391-9412

	MAIL ADDRESS:	
		STREET 1:		C/O ISCO INTERNATIONAL, INC.
		STREET 2:		1001 CAMBRIDGE DRIVE
		CITY:			ELK GROVE VILLAGE
		STATE:			IL
		ZIP:			60007
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>edgar.xml
<DESCRIPTION>PRIMARY DOCUMENT
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2007-12-31</periodOfReport>

    <issuer>
        <issuerCik>0000888693</issuerCik>
        <issuerName>ISCO INTERNATIONAL INC</issuerName>
        <issuerTradingSymbol>ISO</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001315197</rptOwnerCik>
            <rptOwnerName>Thode John</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O ISCO INTERNATIONAL, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>1001 CAMBRIDGE DRIVE</rptOwnerStreet2>
            <rptOwnerCity>ELK GROVE VILLAGE</rptOwnerCity>
            <rptOwnerState>IL</rptOwnerState>
            <rptOwnerZipCode>60007</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
                <footnoteId id="F1"/>
            </securityTitle>
            <transactionDate>
                <value>2008-01-11</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>D</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>4500000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>1077500</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value></value>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">As of 12/31/2007, 4,000,000 shares representing performance grants from 2006 and 2007 were forfeited because the issuer's performance targets were not reached.  500,000 shares were terminated due to the termination of Mr. Thode's employment.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>Frank Cesario, Attorney-In-Fact for John S. Thode</signatureName>
        <signatureDate>2008-01-11</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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