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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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 bo5CJO2qEMWH6/24wjA5Ug==

<SEC-DOCUMENT>0001192482-06-000345.txt : 20060630
<SEC-HEADER>0001192482-06-000345.hdr.sgml : 20060630
<ACCEPTANCE-DATETIME>20060630135232
ACCESSION NUMBER:		0001192482-06-000345
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20060616
FILED AS OF DATE:		20060630
DATE AS OF CHANGE:		20060630

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			CALHOUN GEORGE M
		CENTRAL INDEX KEY:			0001169746

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-22302
		FILM NUMBER:		06936813

	BUSINESS ADDRESS:	
		STREET 1:		329 W 108TH ST
		STREET 2:		4B
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10025

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ISCO INTERNATIONAL INC
		CENTRAL INDEX KEY:			0000888693
		STANDARD INDUSTRIAL CLASSIFICATION:	INSTRUMENTS FOR MEAS & TESTING OF ELECTRICITY & ELEC SIGNALS [3825]
		IRS NUMBER:				363688459
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		451 KINGSTON CT
		CITY:			MOUNT PROSPECT
		STATE:			IL
		ZIP:			60056
		BUSINESS PHONE:		8473919400

	MAIL ADDRESS:	
		STREET 1:		451 KINGSTON COURT
		CITY:			MT PROSPECT
		STATE:			IL
		ZIP:			60056
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>edgar.xml
<DESCRIPTION>PRIMARY DOCUMENT
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2006-06-16</periodOfReport>

    <issuer>
        <issuerCik>0000888693</issuerCik>
        <issuerName>ISCO INTERNATIONAL INC</issuerName>
        <issuerTradingSymbol>ISO</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001169746</rptOwnerCik>
            <rptOwnerName>CALHOUN GEORGE M</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O ISCO INTERNATIONAL, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>1001 CAMBRIDGE DRIVE</rptOwnerStreet2>
            <rptOwnerCity>ELK GROVE VILLAGE</rptOwnerCity>
            <rptOwnerState>IL</rptOwnerState>
            <rptOwnerZipCode>60007</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
                <footnoteId id="F1"/>
            </securityTitle>
            <transactionDate>
                <value>2006-06-16</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>37500</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                    <footnoteId id="F2"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>120250</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value></value>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">Restricted shares awarded to Mr. Calhoun which will vest in four equal installments of 9,375 shares on each of September 15, 2006, December 15, 2006, March 15, 2007 and June 15, 2007.</footnote>
        <footnote id="F2">Mr. Calhoun did not pay for the shares in question; they were awarded to him pursuant to the Issuer's non-employee director compensation policy.  25,000 shares were awarded for his service as a Board member and 12,500 were awarded for his service as Chairman of the Audit Committee.  The  closing price of the subject shares on June 16, 2006 was $0.32 per share.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>Frank Cesario, Attorney-In-Fact for George Calhoun</signatureName>
        <signatureDate>2006-06-30</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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