CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($) shares in Thousands, $ in Thousands	12 Months Ended
	Dec. 31, 2018	Dec. 31, 2017	Dec. 31, 2016
Income Statement [Abstract]
Product sales, net	$ 90,857	$ 62,760	$ 54,383
Other	0	1,164	0
Total revenue	90,857	63,924	54,383
Cost of product sales	32,160	30,354	28,307
Gross profit	58,697	33,570	26,076
Research and development	13,599	12,944	15,295
Selling, general and administrative	49,007	35,610	27,388
Loss on impairment of intangible asset	0	0	2,638
Total operating expenses	62,606	48,554	45,321
Loss from operations	(3,909)	(14,984)	(19,245)
Other income (expense):
Increase in fair value of warrants	(2,524)	(257)	0
Loss on extinguishment of debt	(838)	(860)	0
Interest income	897	14	8
Interest expense	(1,732)	(1,107)	(314)
Other income (expense)	(31)	(92)	(15)
Total other (expense) income	(4,228)	(2,302)	(321)
Net loss	$ (8,137)	$ (17,286)	$ (19,566)
Net loss per share attributable to common shareholders (Basic and Diluted) (in dollars per share)		$ (0.52)	$ (1.18)
Weighted average number of common shares outstanding (Basic and Diluted) (in shares)	40,242	33,355	23,093