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Shareholders' Equity (Details)
12 Months Ended
Dec. 23, 2015
USD ($)
shares
Dec. 18, 2015
shares
Sep. 17, 2014
USD ($)
$ / shares
shares
Jul. 09, 2014
USD ($)
warrant_holder
$ / shares
shares
Jan. 21, 2014
USD ($)
$ / shares
shares
Aug. 16, 2013
USD ($)
$ / shares
shares
Jun. 16, 2011
USD ($)
Dec. 31, 2015
USD ($)
$ / shares
shares
Dec. 31, 2014
USD ($)
$ / shares
shares
Jul. 31, 2015
shares
Shareholders' Equity                    
Number of common shares sold | shares     15,784,313              
Offering price (in dollars per share) | $ / shares     $ 2.55              
Proceeds from issuance of common stock | $     $ 37,500,000     $ 8,200,000        
Number of shares of common stock sold | shares               23,789,000 23,786,000  
Underwriter's discount | $     2,400,000              
Issuance cost | $     $ 300,000              
Series A Convertible Preferred Stock                    
Shareholders' Equity                    
Shares issued upon conversion | shares 1,250 1,250                
MLV                    
Shareholders' Equity                    
Proceeds from issuance of common stock | $               $ 7,100,000 $ 4,800,000  
Amount of net capacity remaining on the ATM | $               $ 7,800,000    
Lincoln Park                    
Shareholders' Equity                    
Proceeds from issuance of common stock | $                 $ 3,700,000  
Period over which shares of common stock to be purchased         30 months          
Floor price for sale of shares of common stock (in dollars per share) (less than) | $ / shares         $ 2.50          
Number of shares of common stock sold | shares                 935,499  
August 2013 warrants                    
Shareholders' Equity                    
Number of shares purchased on exercise of warrants | shares       362,500       724,950   226,299
Offering price (in dollars per share) | $ / shares               $ 2.58 $ 3.04  
Number of warrant holders | warrant_holder       1            
Exercise price of warrants (in dollars per share) | $ / shares       $ 4.80       $ 4.80    
Net proceeds from exercise of warrants | $       $ 1,500,000            
Maximum | MLV                    
Shareholders' Equity                    
Expected proceeds from sale of common stock | $             $ 20,300,000.0      
Percentage of gross proceeds payable as commission             3.00%      
Maximum | Lincoln Park                    
Shareholders' Equity                    
Value of shares of common stock to be sold | $         $ 15,000,000.0          
Number of shares of common stock to be purchased in regular purchases | shares         50,000          
Number of shares of common stock to be purchased depending upon the closing sale price of the common stock | shares         100,000          
Period of business days over which purchase price of shares of common stock will be determined         10 days          
Threshold on percentage of outstanding shares of the common stock that can be beneficially owned by counterparty (more than)               9.99%    
Value of remaining shares of common stock to be sold | $                 $ 11,300,000  
Minimum | Lincoln Park                    
Shareholders' Equity                    
Threshold closing sale price of the common stock on the date of a regular purchase to trigger purchase of additional amounts as accelerated purchases (in dollars per share) (equals or exceeds) | $ / shares         $ 3.00          
Common Stock                    
Shareholders' Equity                    
Number of common shares sold | shares           1,500,000.0     18,655,000  
Stock issued to underwriter for exercise of over allotment option (in shares) | shares           50,000        
Offering price (in dollars per share) | $ / shares           $ 6.00        
Shares converted | shares 1,250,000 1,250,000                
Shares issued upon conversion | shares               3,000 408,000  
Conversion of stock, amount converted | $ $ 3,200,000                  
Warrants                    
Shareholders' Equity                    
Fair market value of the warrants | $           $ 5,900,000        
Warrants | Maximum                    
Shareholders' Equity                    
Number of shares purchased on exercise of warrants | shares           1,500,000.0