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Amount of investment in equity method investee and investment in and advance to affiliate.

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JOINT VENTURE FOR DEVELOPMENT OF APO E MIMETIC PEPTIDE MOLECULE AEM-28 AND ANALOGS (Details Textual) - USD ($)				1 Months Ended				3 Months Ended		12 Months Ended	77 Months Ended
	Aug. 11, 2017	Jul. 14, 2017	Aug. 03, 2012	Oct. 27, 2017	Aug. 31, 2017	Aug. 25, 2016	Mar. 31, 2016	Mar. 31, 2019	Mar. 31, 2018	Dec. 31, 2018	Dec. 31, 2018
Related Party Transaction [Line Items]
Investments in and Advance to Affiliates, Subsidiaries, Associates, and Joint Ventures			$ 6,000,000					$ 6,000,000
Joint Venture Investments In Voting Common Ownership Units (in shares)			600,000
Joint Venture Investments In Non Voting Preferred Ownership Units			5,000,000
Joint Venture, Operating Expenses, Inter Company Transactions								684,000			$ 10,282,000
Joint Venture, Operating Expenses Allocated To Company											8,670,000
Percentage Of Non Royalty Income	5.00%		5.00%
Conversion of Stock, Shares Converted	(3,500,000)
Conversion of Stock, Shares Issued							120,000
Joint Venture Method Investment Ownership Percentage			60.00%
Proceeds from Issuance of Preferred Stock and Preference Stock								0
Class of Warrant or Right, Number of Securities Called by Warrants or Rights						33,088
Class of Warrant or Right, Exercise Price of Warrants or Rights						$ 10.70
Management Fees								50,000
Operating Expenses Net Of Elimination Of Intercompany Transactions								684,000
Conversion of Stock, Amount Converted	$ 3,500,000
Conversion of Stock, Amount Issued	$ 1,000,000
Interest Payable								$ 249,000		$ 213,000	$ 213,000
Accrued Professional Fees					$ 20,000
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant										83,480	83,480
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross				14,126
Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price				$ 10.70
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Rights, Percentage										50.00%
Ownership As Converted [Member]
Related Party Transaction [Line Items]
Joint Venture Method Investment Ownership Percentage										65.11%
Ownership As Converted Including Options And Warrants [Member]
Related Party Transaction [Line Items]
Joint Venture Method Investment Ownership Percentage				64.31%
Joint Venture [Member]
Related Party Transaction [Line Items]
Noncontrolling Interest, Ownership Percentage by Parent								100.00%
Series B1 Preferred Stock [Member]
Related Party Transaction [Line Items]
Joint Venture Losses Recognition Criteria, Common Ownership Equity						$ 946,000
Proceeds From Issuance Of Preferred Stock Before Adjusted Stock Issuance Costs						1,012,000
Proceeds from Issuance of Preferred Stock and Preference Stock						946,000
Payments of Stock Issuance Costs						$ 66,000
Stock Issued During Period, Shares, New Issues						94,537
Management Fees					$ 300,000
Management Fee Expense								$ 150,000	$ 150,000
Accrued Professional Fees								400,000
Series B2 Preferred Stock [Member]
Related Party Transaction [Line Items]
Joint Venture Losses Recognition Criteria, Common Ownership Equity						$ 946,000
Proceeds From Issuance Of Preferred Stock Before Adjusted Stock Issuance Costs						$ 1,012,000
Proceeds from Issuance of Preferred Stock and Preference Stock								946,000
Payments of Stock Issuance Costs		$ 287,000
Stock Issued During Period, Shares, Acquisitions	93,458				93,458	93,458
Stock Issued During Period, Value, Acquisitions	$ 1,000,000				$ 1,000,000	$ 1,000,000
Adjustments to Additional Paid in Capital, Stock Issued, Issuance Costs	$ 15,000
Series B1 And B2 Preferred Stock [Member]
Related Party Transaction [Line Items]
Joint Venture Method Investment Ownership Percentage			62.20%
Series A Preferred Stock [Member]
Related Party Transaction [Line Items]
Joint Venture Method Investment Ownership Percentage			69.75%
Revolving Credit Facility [Member]
Related Party Transaction [Line Items]
Long-term Line of Credit								1,740,000
Interest Payable								140,000
Preferred Stock [Member]
Related Party Transaction [Line Items]
Conversion of Stock, Shares Converted							1,500,000
Noncontrolling Interest [Member]
Related Party Transaction [Line Items]
Noncash or Part Noncash Acquisition, Other Liabilities Assumed											$ 667,000
Maximum [Member]
Related Party Transaction [Line Items]
Joint Venture Method Investment Ownership Percentage							64.00%
Minimum [Member]
Related Party Transaction [Line Items]
Joint Venture Method Investment Ownership Percentage							60.00%
Exclusive License Agreement [Member]
Related Party Transaction [Line Items]
Percentage Of Royalty Payment						3.00%
Annual Maintenance Payments						$ 25,000
Exclusive License Agreement [Member] \| Maximum [Member]
Related Party Transaction [Line Items]
Milestone Payments						500,000
Royalty Expense			$ 1,000,000
Exclusive License Agreement [Member] \| Minimum [Member]
Related Party Transaction [Line Items]
Milestone Payments						$ 50,000
Royalty Expense			$ 500,000
Lipimetix [Member]
Related Party Transaction [Line Items]
Joint Venture Investments Common Ownership Units, Co-venture (in shares)			400,000
Ownership Percentage Co-venture			40.00%
Noncash or Part Noncash Acquisition, Other Liabilities Assumed								667,000
Noncash or Part Noncash Acquisition, Net Nonmonetary Assets Acquired (Liabilities Assumed)			$ 378,000					$ 378,000
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross										81,479
Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price										$ 1.07
Voting Common Ownership Units [Member]
Related Party Transaction [Line Items]
Investments in and Advance to Affiliates, Subsidiaries, Associates, and Joint Ventures			1,000,000
Non Voting Preferred Ownership Units [Member]
Related Party Transaction [Line Items]
Investments in and Advance to Affiliates, Subsidiaries, Associates, and Joint Ventures			$ 5,000,000