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Ownership percentage of co- venture.

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Amount of interest payable on debt, including, but not limited to, trade payables.

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Amount of investment in equity method investee and investment in and advance to affiliate.

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Amount of expenses related to the managing member or general partner for management of the day-to-day business functions of the limited liability company (LLC) or limited partnership (LP).

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The parent entity's interest in net assets of the subsidiary, expressed as a percentage.

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Amount of liabilities, classified as other, assumed in acquiring a business or in consideration for an asset received in a noncash or part noncash acquisition.

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Amount paid to managing member or general partner for management of the day-to-day business functions of the limited liability company (LLC) or limited partnership (LP).

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The cash outflow for cost incurred directly with the issuance of an equity security.

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JOINT VENTURE FOR DEVELOPMENT OF APO E MIMETIC PEPTIDE MOLECULE AEM-28 AND ANALOGS (Details Textual) - USD ($)				1 Months Ended							12 Months Ended			77 Months Ended
	Aug. 11, 2017	Jul. 14, 2017	Aug. 03, 2012	Jan. 01, 2019	Apr. 30, 2018	Oct. 27, 2017	Aug. 31, 2017	Aug. 25, 2016	Jun. 01, 2016	Mar. 31, 2016	Dec. 31, 2018	Dec. 31, 2017	Dec. 31, 2016	Dec. 31, 2018	Jan. 30, 2018
Related Party Transaction [Line Items]
Investments in and Advance to Affiliates, Subsidiaries, Associates, and Joint Ventures			$ 6,000,000								$ 6,000,000			$ 6,000,000
Joint Venture Investments In Voting Common Ownership Units (in shares)			600,000
Joint Venture Investments In Non Voting Preferred Ownership Units			5,000,000
Development Activities Monthly Fee			$ 63,000
Joint Venture, Operating Expenses, Inter Company Transactions											53,000			9,598,000
Joint Venture, Operating Expenses Allocated To Company														7,985,000
Percentage Of Non Royalty Income			5.00%
Long-term Line of Credit											1,720,000			$ 1,720,000
Conversion of Stock, Shares Converted	3,500,000									1,500,000
Conversion of Stock, Shares Issued										120,000
Joint Venture Method Investment Ownership Percentage			60.00%
Proceeds from Issuance of Preferred Stock and Preference Stock											$ 0	$ (15,000)	$ 946,000
Class of Warrant or Right, Number of Securities Called by Warrants or Rights								33,088			6,321,930			6,321,930
Class of Warrant or Right, Exercise Price of Warrants or Rights								$ 10.70							$ 0.075
Management Fees					$ 50,000				$ 80,000
Professional Fees									$ 10,000
Operating Expenses Net Of Elimination Of Intercompany Transactions											$ 53,000
Conversion of Stock, Amount Converted	$ 3,500,000
Conversion of Stock, Amount Issued	$ 1,000,000
Interest Payable											213,000	68,000		$ 213,000
Other Assets, Current											$ 97,000	$ 98,000		$ 97,000
Accrued Professional Fees							$ 20,000
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant											83,480			83,480
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross						14,126					0	0
Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price						$ 10.70						$ 0.37
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Rights, Percentage											50.00%
Payment for Management Fee				$ 50,000
Mr Holliman [Member]
Related Party Transaction [Line Items]
Share-based Compensation Arrangement by Share-based Payment Award, Expiration Period											5 years
Ownership As Converted [Member]
Related Party Transaction [Line Items]
Joint Venture Method Investment Ownership Percentage											65.11%
Ownership As Converted Including Options And Warrants [Member]
Related Party Transaction [Line Items]
Joint Venture Method Investment Ownership Percentage						64.31%
Series B1 Preferred Stock [Member]
Related Party Transaction [Line Items]
Proceeds From Issuance Of Preferred Stock Before Adjusted Stock Issuance Costs								$ 1,012,000
Proceeds from Issuance of Preferred Stock and Preference Stock								946,000
Payments of Stock Issuance Costs								$ 66,000
Stock Issued During Period, Shares, New Issues								94,537
Management Fees							$ 300,000						300,000
Professional Fees													60,000
Management Fee Expense											$ 150,000	$ 150,000	250,000
Other Assets, Current													$ 50,000
Accrued Professional Fees											$ 340,000			$ 340,000
Series B2 Preferred Stock [Member]
Related Party Transaction [Line Items]
Payments of Stock Issuance Costs		$ 287,000
Stock Issued During Period, Shares, Acquisitions	93,458						93,458	93,458
Stock Issued During Period, Value, Acquisitions	$ 1,000,000						$ 1,000,000	$ 1,000,000
Adjustments to Additional Paid in Capital, Stock Issued, Issuance Costs	$ 15,000
Series B Preferred Stock [Member] \| Preferred Stock And Warrant Purchase Agreement [Member]
Related Party Transaction [Line Items]
Preferred Stock, Dividend Rate, Percentage								5.00%
Series B1 And B2 Preferred Stock [Member]
Related Party Transaction [Line Items]
Joint Venture Method Investment Ownership Percentage			62.20%
Series A Preferred Stock [Member]
Related Party Transaction [Line Items]
Joint Venture Method Investment Ownership Percentage			69.75%
Preferred Stock [Member] \| Ownership As Converted [Member]
Related Party Transaction [Line Items]
Noncontrolling Interest, Ownership Percentage by Parent											100.00%			100.00%
Noncontrolling Interest [Member]
Related Party Transaction [Line Items]
Noncash or Part Noncash Acquisition, Other Liabilities Assumed														$ 667,000
Maximum [Member]
Related Party Transaction [Line Items]
Joint Venture Method Investment Ownership Percentage										64.00%
Minimum [Member]
Related Party Transaction [Line Items]
Joint Venture Method Investment Ownership Percentage										60.00%
Exclusive License Agreement [Member]
Related Party Transaction [Line Items]
Percentage Of Royalty Payment								3.00%
Annual Maintenance Payments								$ 25,000
Exclusive License Agreement [Member] \| Maximum [Member]
Related Party Transaction [Line Items]
Milestone Payments								500,000
Royalty Expense			$ 1,000,000
Exclusive License Agreement [Member] \| Minimum [Member]
Related Party Transaction [Line Items]
Milestone Payments								$ 50,000
Royalty Expense			$ 500,000
Lipimetix [Member]
Related Party Transaction [Line Items]
Joint Venture Investments Common Ownership Units, Co-venture (in shares)			400,000
Ownership Percentage Co-venture			40.00%
Noncash or Part Noncash Acquisition, Other Liabilities Assumed											$ 667,000
Noncash or Part Noncash Acquisition, Net Nonmonetary Assets Acquired (Liabilities Assumed)			$ 378,000								$ 378,000
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross											81,479
Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price											$ 1.07
Voting Common Ownership Units [Member]
Related Party Transaction [Line Items]
Investments in and Advance to Affiliates, Subsidiaries, Associates, and Joint Ventures			1,000,000
Non Voting Preferred Ownership Units [Member]
Related Party Transaction [Line Items]
Investments in and Advance to Affiliates, Subsidiaries, Associates, and Joint Ventures			$ 5,000,000