CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (USD $) In Thousands, unless otherwise specified	3 Months Ended		104 Months Ended
	Mar. 31, 2013	Mar. 31, 2012	Mar. 31, 2013
OPERATING ACTIVITIES
Net loss	$ (1,188)	$ (976)	$ (151,634)
Non cash items:
Deferred tax expense	0	0	770
Depreciation and amortization, net of gain on sale	45	24	4,016
Non-cash stock compensation	17	28	4,948
Gain on sale of bone device business	0	0	(2,298)
In-process research and development	0	0	34,311
Change in other operating items:
Interest, income taxes and other current assets	78	226	1,404
Accounts payable	80	67	(658)
Accrued liabilities	(40)	(30)	(2,996)
Cash flows used in operating activities	(1,008)	(661)	(112,137)
INVESTING ACTIVITIES
Expenditures for furniture and equipment, net	0	0	(1,044)
Proceeds from sale of assets	4	0	7,176
Cash paid for assets of AzERx/CBI	0	0	(4,058)
Cash paid for patent rights	0	0	(1,028)
Purchases of investments	0	0	(282,538)
Maturities of investments	0	0	340,476
Cash flows provided by investing activities	4	0	58,984
FINANCING ACTIVITIES
Net proceeds from stock option exercises	0	0	4,612
Net proceeds from sale of stock	0	0	3,376
Common stock purchases	0	0	(1,041)
Cash flows provided by financing activities	0	0	6,947
NET DECREASE IN CASH AND CASH EQUIVALENTS	(1,004)	(661)	(46,206)
CASH AND CASH EQUIVALENTS, BEGINNING OF PERIOD	10,205	13,778	55,407
CASH AND CASH EQUIVALENTS, END OF PERIOD	9,201	13,117	9,201
Supplemental Disclosure of Non-Cash Investing Activities -
Cash paid	0	0	4,058
Lipimetix [Member]
INVESTING ACTIVITIES
Cash paid for assets of AzERx/CBI			(4,436)
Supplemental Disclosure of Non-Cash Investing Activities -
Current assets acquired			29
Patent rights acquired			3,187
Liabilities acquired, and accrued acquisition costs			(457)
Original investment reversal			(750)
In-process research and development acquired			34,311
Noncontrolling interest			(667)
Common stock issued for acquisition			(31,217)
Cash paid			$ 4,436