CONDENSED STATEMENTS OF CASH FLOWS (USD $) In Thousands, unless otherwise specified	3 Months Ended		92 Months Ended
	Mar. 31, 2012	Mar. 31, 2011	Mar. 31, 2012
OPERATING ACTIVITIES
Net loss	$ (976)	$ (3,237)	$ (147,368)
Non cash items:
Deferred tax expense	0	0	770
Depreciation and amortization	24	32	3,966
Non-cash stock compensation	28	67	4,852
Gain on sale of bone device business	0	0	(2,298)
In-process research and development	0	0	34,311
Change in other operating items:
Interest, income taxes and other current assets	226	180	1,176
Accounts payable	67	386	(827)
Accrued liabilities	(30)	(175)	(3,005)
Cash flows used in operating activities	(661)	(2,747)	(108,423)
INVESTING ACTIVITIES
Expenditures for furniture and equipment, net	0	0	(1,044)
Proceeds from sale of assets	0	0	7,000
Cash paid for assets of AzERx/CBI	0	0	(4,058)
Cash paid for patent assignment rights	0	0	(650)
Purchases of investments	0	0	(282,538)
Maturities of investments	0	0	340,476
Cash flows provided by investing activities	0	0	59,186
FINANCING ACTIVITIES
Net proceeds from stock option exercises	0	0	4,612
Net proceeds from sale of stock	0	0	3,376
Common stock purchases	0	0	(1,041)
Cash flows provided by financing activities			6,947
NET DECREASE IN CASH AND CASH EQUIVALENTS	(661)	(2,747)	(42,290)
CASH AND CASH EQUIVALENTS, BEGINNING OF PERIOD	13,778	24,387	55,407
CASH AND CASH EQUIVALENTS, END OF PERIOD	13,117	21,640	13,117
Supplemental Disclosure of Non-Cash Investing Activities -
Current assets acquired			29
Patents acquired			2,142
Liabilities acquired, and accrued acquisition costs			(457)
Original investment reversal			(750)
In-process research and development acquired			34,311
Common stock issued for acquisition			(31,217)
Cash paid for acquisition	$ 0	$ 0	$ 4,058