CONDENSED STATEMENTS OF CASH FLOWS (USD $) In Thousands	9 Months Ended		87 Months Ended
	Sep. 30, 2011	Sep. 30, 2010	Sep. 30, 2011
OPERATING ACTIVITIES
Net loss	$ (7,022)	$ (8,455)	$ (143,703)
Non cash items:
Deferred tax expense	0	0	770
Depreciation and amortization	90	101	3,915
Non-cash stock compensation	133	190	4,798
Gain on sale of bone device business	0	0	(2,298)
In-process research and development	0	0	34,311
Change in other operating items:
Interest, income taxes and other current assets	434	1,241	1,499
Accounts payable	91	(327)	(634)
Accrued liabilities	(486)	(672)	(2,590)
Cash flows used in operating activities	(6,760)	(7,922)	(103,932)
INVESTING ACTIVITIES
Expenditures for furniture and equipment, net	(19)	(60)	(1,044)
Proceeds from sale of assets	0	0	7,000
Cash paid for assets of AzERx/CBI			(4,058)
Cash paid for patent assignment rights	0	0	(650)
Purchases of investments	0	(25,140)	(282,538)
Maturities of investments	0	31,941	340,476
Cash flows (used in) provided by investing activities	(19)	6,741	59,186
FINANCING ACTIVITIES
Net proceeds from stock option exercises	0	0	4,612
Net proceeds from sale of stock	0	0	3,376
Common stock purchases	0	0	(1,041)
Cash flows provided by financing activities	0	0	6,947
NET DECREASE IN CASH AND CASH EQUIVALENTS	(6,779)	(1,181)	(37,799)
CASH AND CASH EQUIVALENTS, BEGINNING OF PERIOD	24,387	12,874	55,407
CASH AND CASH EQUIVALENTS, END OF PERIOD	$ 17,608	$ 11,693	$ 17,608