CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)	9 Months Ended
	Sep. 30, 2022	Sep. 30, 2021
Cash flows from operating activities:
Net loss	$ (99,266,000)	$ (84,095,000)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	208,000	154,000
Accretion and amortization on investments, net	(9,000)	1,137,000
Amortization of debt issuance costs/debt discount	1,103,000	627,000
Gain on sales of equity investment		(1,233,000)
Stock-based compensation for services by non-employees	140,000	71,000
Stock-based compensation for employees and directors	5,813,000	5,775,000
Amortization of right-of-use assets	431,000	403,000
Changes in assets and liabilities:
Current and noncurrent assets	(24,506,000)	(3,363,000)
Current and noncurrent liabilities	23,888,000	7,136,000
Net cash used in operating activities	(92,198,000)	(73,388,000)
Cash flows from investing activities:
Purchases of property and equipment	(291,000)	(104,000)
Purchases of marketable securities	(97,336,000)	(116,482,000)
Proceeds from maturities of marketable securities	140,706,000	178,574,000
Proceeds from sales of equity investment		1,594,000
Net cash provided by investing activities	43,079,000	63,582,000
Cash flows from financing activities:
Proceeds from issuances of common stock from equity plans	1,962,000	204,000
Proceeds from issuance of common stock and warrants in public offering, net of paid issuance costs	69,916,000
Proceeds from issuances of common stock from at market offerings, net of paid issuance costs		16,234,000
Proceeds from exercise of warrants	3,638,000	2,479,000
Proceeds from debt financing		10,000,000
Debt discount and issuance costs for debt financing	(175,000)
Net cash provided by financing activities	75,341,000	28,917,000
Net effect of unrealized losses and exchange rates on cash, cash equivalents and restricted cash	10,000
Net change in cash, cash equivalents and restricted cash	26,232,000	19,111,000
Cash, cash equivalents and restricted cash at the beginning of the period	35,235,000	10,288,000
Cash, cash equivalents and restricted cash at the end of the period	$ 61,467,000	$ 29,399,000