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SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES - BASIS OF PRESENTATION (Details) - USD ($)
3 Months Ended 9 Months Ended
Apr. 01, 2022
Sep. 30, 2022
Jun. 30, 2022
Mar. 31, 2022
Sep. 30, 2021
Jun. 30, 2021
Mar. 31, 2021
Sep. 30, 2022
Sep. 30, 2021
Dec. 31, 2021
Net loss   $ (41,051,000) $ (28,117,000) $ (30,098,000) $ (26,697,000) $ (29,574,000) $ (27,824,000) $ (99,266,000) $ (84,095,000)  
Cash flows from operations               (92,198,000) $ (73,388,000)  
Accumulated deficit   (1,371,007,000)           (1,371,007,000)   $ (1,271,741,000)
Cash, restricted cash, cash equivalents, and marketable securities.   $ 195,151,000           $ 195,151,000    
2022 Underwritten Public Offering                    
Issuance of common stock in connection with public offering (in shares) 53,333,334                  
Net cash proceeds from public offering after deducting underwriting discount and other offering expenses $ 69,916,000                  
2022 Underwritten Public Offering | 2022 Pre-Funded Warrant                    
Warrant to purchase common stock, shares 18,095,238                  
2022 Underwritten Public Offering | 2022 Stock Purchase Warrants                    
Warrant to purchase common stock, shares 35,714,286