POWER OF ATTORNEY
             SEC FORMS 3, 4 and 5


The undersigned, Taylor J. Crouch, hereby appoints
and designates each of Warner R. Broaddus, Paul V.
Maier and Barbara J. Olson his/her attorney-in-fact,
signing singly, to execute and file on the
undersigned's behalf all Forms 3, 4, and 5 (including
any amendments thereto) that the undersigned may be
required to file with the U.S. Securities and
Exchange Commission as a result of the undersigned's
ownership of or transactions in securities of Ligand
Pharmaceuticals Incorporated.  Any previous authority
to act on the undersigned's behalf in connection with
such execution and filing of Forms 3, 4 and 5 is
hereby revoked and the authority of Warner R.
Broaddus, Paul V. Maier and Barbara J. Olson under
this Statement shall continue until the undersigned
is no longer required to file Forms 3, 4 and 5 with
regard to the undersigned's ownership of or
transactions in securities of Ligand Pharmaceuticals
Incorporated, unless earlier revoked in writing. The
undersigned acknowledges that neither Warner R.
Broaddus, Paul V. Maier nor Barbara J. Olson is
assuming any of the undersigned's responsibilities to
comply with Section 16 of the Securities Exchange Act
of 1934.



Date:  July 28, 2005        /s/ Taylor J. Crouch
                                Taylor J. Crouch