Basis of Presentation and Summary of Significant Accounting Policies - Accounting for Share-Based Compensation (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2023	Jun. 30, 2022	Jun. 30, 2023	Jun. 30, 2022
Basis of Presentation [Line Items]
Share-based compensation expense	$ 7,207	$ 7,001	$ 13,138	$ 14,110
SBC - Research and development expenses
Basis of Presentation [Line Items]
Share-based compensation expense	2,016	2,447	3,723	4,643
SBC - General and administrative expenses
Basis of Presentation [Line Items]
Share-based compensation expense	$ 5,191	$ 4,554	$ 9,415	$ 9,467