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Stockholders' Equity - Stock Option Plan and Restricted Stock Activity (Details)
6 Months Ended
Jun. 30, 2022
$ / shares
shares
Stock Options  
Shares  
Balance at beginning of period (shares) | shares 2,199,598
Granted (shares) | shares 734,218
Options exercised (shares) | shares (25,798)
Forfeited (shares) | shares (30,417)
Balance at end of period (shares) | shares 2,877,601
Weighted-Average Exercise Price  
Balance at beginning of period (USD per share) | $ / shares $ 106.00
Granted (USD per share) | $ / shares 91.58
Options exercised (USD per share) | $ / shares 20.53
Forfeited (USD per share) | $ / shares 67.60
Balance at end of period (USD per share) | $ / shares $ 103.50
Restricted Stock Awards  
Restricted Stock Awards  
Nonvested at beginning of period (shares) | shares 264,143
Granted (shares) | shares 186,526
RSUs vested (shares) | shares (133,173)
Forfeited (shares) | shares (1,378)
Nonvested at end of period (shares) | shares 316,118
Weighted-Average Grant Date Fair Value  
Nonvested at beginning of period (USD per share) | $ / shares $ 138.21
Granted (USD per share) | $ / shares 87.32
RSUs vested (USD per share) | $ / shares 120.66
Forfeited (USD per share) | $ / shares 137.16
Nonvested at end of period (USD per share) | $ / shares $ 115.58