CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021
Revenues:
Total revenues	$ 57,419	$ 84,675	$ 103,112	$ 139,825
Operating costs and expenses:
Cost of Captisol	12,361	30,593	17,060	38,746
Amortization of intangibles	11,824	11,779	23,637	23,565
Research and development	19,118	15,953	39,425	33,832
General and administrative	14,585	14,711	32,765	27,028
Other operating income	0	(34,100)	0	(33,800)
Total operating costs and expenses	57,888	38,936	112,887	89,371
Income (loss) from operations	(469)	45,739	(9,775)	50,454
Other income (expense):
Gain (loss) from short-term investments	(1,909)	(6,864)	(14,786)	6,197
Interest income	298	233	432	529
Interest expense	(438)	(4,883)	(1,227)	(10,714)
Other income (expense), net	1,882	(924)	4,580	(7,401)
Total other expense, net	(167)	(12,438)	(11,001)	(11,389)
Income (loss) before income taxes	(636)	33,301	(20,776)	39,065
Income tax benefit (expense)	(259)	(2,576)	4,496	9,766
Net (loss) income	$ (895)	$ 30,725	$ (16,280)	$ 48,831
Earnings per share
Basic net (loss) income per share (USD per share)	$ (0.05)	$ 1.84	$ (0.97)	$ 2.95
Shares used in basic per share calculations (shares)	16,868	16,659	16,846	16,548
Diluted net (loss) income per share (USD per share)	$ (0.05)	$ 1.79	$ (0.97)	$ 2.84
Shares used in diluted per share calculations (shares)	16,868	17,172	16,846	17,210
Royalties
Revenues:
Total revenues	$ 17,959	$ 8,616	$ 31,654	$ 15,728
Captisol
Revenues:
Total revenues	29,545	62,509	41,667	93,781
Contract
Revenues:
Total revenues	$ 9,915	$ 13,550	$ 29,791	$ 30,316