Convertible Senior Notes - Narrative (Details)	1 Months Ended		3 Months Ended		12 Months Ended
	Jan. 31, 2021 USD ($)	May 31, 2018 USD ($) d $ / shares shares	Mar. 31, 2022 USD ($)	Mar. 31, 2021 USD ($)	Dec. 31, 2021 USD ($) option shares
Debt Instrument [Line Items]
Gain on extinguishment of debt			$ 1,532,000	$ (4,840,000)
Adjustments to additional paid-in-capital from warrants					$ 500,000
Payments to unwind warrants					18,400,000
Proceeds from unwinding convertible bond hedges					$ 18,900,000
Number of options under convertible bond hedges | option					598,021
Convertible Notes | 2023 Convertible Senior Notes
Debt Instrument [Line Items]
Interest rate (as a percent)		0.75%
Aggregate principal amount outstanding		$ 750,000,000	177,527,000		$ 343,301,000
Proceeds from debt, net of issuance costs		$ 733,100,000
Initial conversion rate (shares per $1,000)		0.0040244
Initial conversion price (USD per share) | $ / shares		$ 248.48
Debt issuance costs			$ 16,900,000
Term of debt instrument			5 years
Effective interest rate (as a percent)			0.50%
Total interest expense			$ 800,000
Contractual interest expense			500,000
Amortized issuance costs			300,000
Repurchased amount of debt instrument	$ 20,300,000		165,800,000		152,000,000
Repayments of notes	19,100,000		163,700,000		156,000,000
Accrued interest portion of repurchased amount of debt instrument	$ 100,000		400,000		300,000
Outstanding principal amount of debt					$ 343,300,000
Gain on extinguishment of debt			1,500,000
Increase (decrease) in debt discount			$ 900,000
Warrants issued in public offering (shares) | shares		3,018,327			2,559,254
Payments for convertible bond hedges		$ 140,300,000
Warrant exercise price (USD per share) | $ / shares		$ 315.38
Adjustments to additional paid-in-capital from warrants		$ 90,000,000
Accrued Interest					$ 300,000
Convertible Notes | 2023 Convertible Senior Notes | Maximum
Debt Instrument [Line Items]
Initial conversion rate (shares per $1,000)		0.0052317
Initial conversion price (USD per share) | $ / shares		$ 191.14
Convertible Notes | 2023 Convertible Senior Notes | Debt Instrument, Redemption, Period One
Debt Instrument [Line Items]
Threshold trading days | d		20
Consecutive trading days | d		30
Stock price trigger to classify convertible debt as current (as a percent)		130.00%
Convertible Notes | 2023 Convertible Senior Notes | Debt Instrument, Redemption, Period Two
Debt Instrument [Line Items]
Threshold trading days | d		5
Consecutive trading days | d		10
Maximum threshold of debt trading price trigger (as a percent)		98.00%