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Basis of Presentation and Summary of Significant Accounting Policies - Narrative (Details) - USD ($)
$ / shares in Units, shares in Thousands
1 Months Ended 3 Months Ended 9 Months Ended
Aug. 16, 2019
Aug. 15, 2019
May 31, 2019
Dec. 31, 2018
Sep. 30, 2019
Jun. 30, 2019
Sep. 30, 2018
Sep. 30, 2019
Sep. 30, 2018
Jan. 01, 2019
Mar. 31, 2018
Dec. 31, 2017
Property, Plant and Equipment [Line Items]                        
Cash flows provided by operating activities               $ (21,997,000) $ 161,487,000      
Cash flows used in financing activities               (401,479,000) $ 675,670,000      
Right-of-use assets       $ 0 $ 10,280,000     10,280,000        
Lease liabilities         10,858,000     10,858,000        
Revenue recognized from milestone method revenue         1,000,000.0     5,000,000.0        
Investment in Viking common stock       46,191,000 41,542,000     41,542,000        
Total assets       656,665,000 $ 924,239,000     $ 924,239,000        
Potentially dilutive shares excluded from calculation due to anti-dilutive effect (shares)         11,549   3,126 8,694 1,789      
Share-based Compensation                        
Property, Plant and Equipment [Line Items]                        
Potentially dilutive shares excluded from calculation due to anti-dilutive effect (shares)         700              
Level 1                        
Property, Plant and Equipment [Line Items]                        
Investment in Viking common stock       46,191,000 $ 41,542,000     $ 41,542,000        
Total assets       56,774,000 $ 52,027,000     $ 52,027,000        
Viking Therapeutics, Inc.                        
Property, Plant and Equipment [Line Items]                        
Equity ownership interest (as a percent)                     12.40%  
Outstanding warrants to purchase shares of Viking's common stock (shares)         1,500     1,500        
Warrant exercise price (USD per share)         $ 1.50     $ 1.50        
Recurring | Level 1 | Investment in Warrants                        
Property, Plant and Equipment [Line Items]                        
Total assets                       $ 9,300,000
Accounting Standards Update 2016-02                        
Property, Plant and Equipment [Line Items]                        
Right-of-use assets                   $ 5,200,000    
Lease liabilities                   $ 5,900,000    
Royalty Agreements | Aziyo                        
Property, Plant and Equipment [Line Items]                        
Effective interest rate for forecasted cash flows (as a percent)               23.00%        
Commercial license rights                        
Property, Plant and Equipment [Line Items]                        
Definite lived intangible assets       36,298,000 $ 50,298,000     $ 50,298,000        
Commercial license rights | Palvella                        
Property, Plant and Equipment [Line Items]                        
Contract asset       8,000,000.0                
Definite lived intangible assets       10,000,000 10,000,000     10,000,000        
Commercial license rights | Novan                        
Property, Plant and Equipment [Line Items]                        
Contract asset     $ 20,000,000.0                  
Definite lived intangible assets     $ 12,000,000.0 $ 0 $ 12,000,000     $ 12,000,000        
Minimum | Royalty Agreements | Palvella                        
Property, Plant and Equipment [Line Items]                        
Tiered royalty rate (as a percent)       5.00%                
Minimum | Royalty Agreements | Novan                        
Property, Plant and Equipment [Line Items]                        
Tiered royalty rate (as a percent)     7.00%                  
Maximum | Royalty Agreements | Palvella                        
Property, Plant and Equipment [Line Items]                        
Tiered royalty rate (as a percent)       9.80%                
Maximum | Royalty Agreements | Novan                        
Property, Plant and Equipment [Line Items]                        
Tiered royalty rate (as a percent)     10.00%                  
2019 Convertible Senior Notes | Convertible Notes                        
Property, Plant and Equipment [Line Items]                        
Debt premium $ 0 $ 11,900,000                    
Repayments of notes $ 0 $ 26,300,000                    
Previously Reported                        
Property, Plant and Equipment [Line Items]                        
Accrued Liabilities       $ 4,600,000                
Restatement Adjustment                        
Property, Plant and Equipment [Line Items]                        
Cash flows provided by operating activities           $ 4,600,000            
Cash flows used in financing activities           $ 4,600,000