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Fair Value Measurements (Details) (USD $)
Sep. 30, 2014
2019 convertible senior notes
Dec. 31, 2013
2019 convertible senior notes
Aug. 31, 2014
2019 convertible senior notes
Senior Notes
Sep. 30, 2014
Recurring
Dec. 31, 2013
Recurring
Sep. 30, 2014
Recurring
Current contingent liabilities-CyDex
Dec. 31, 2013
Recurring
Current contingent liabilities-CyDex
Sep. 30, 2014
Recurring
Current co-promote termination liability
Dec. 31, 2013
Recurring
Current co-promote termination liability
Sep. 30, 2014
Recurring
Long-term contingent liabilities-Metabasis
Dec. 31, 2013
Recurring
Long-term contingent liabilities-Metabasis
Sep. 30, 2014
Recurring
Long-term contingent liabilities-CyDex
Dec. 31, 2013
Recurring
Long-term contingent liabilities-CyDex
Sep. 30, 2014
Recurring
Liability for short-term investments owed to former licensees
Dec. 31, 2013
Recurring
Liability for short-term investments owed to former licensees
Dec. 31, 2013
Recurring
Long-term portion of co-promote termination liability
Sep. 30, 2014
Recurring
Current co-promote termination payments receivable
Dec. 31, 2013
Recurring
Current co-promote termination payments receivable
Sep. 30, 2014
Recurring
Available-for-sale securities
Dec. 31, 2013
Recurring
Available-for-sale securities
Dec. 31, 2013
Recurring
Long-term portion of co-promote termination payments receivable
Sep. 30, 2014
Recurring
Quoted Prices in Active Markets for Identical Assets (Level 1)
Dec. 31, 2013
Recurring
Quoted Prices in Active Markets for Identical Assets (Level 1)
Sep. 30, 2014
Recurring
Quoted Prices in Active Markets for Identical Assets (Level 1)
Current contingent liabilities-CyDex
Dec. 31, 2013
Recurring
Quoted Prices in Active Markets for Identical Assets (Level 1)
Current contingent liabilities-CyDex
Sep. 30, 2014
Recurring
Quoted Prices in Active Markets for Identical Assets (Level 1)
Current co-promote termination liability
Dec. 31, 2013
Recurring
Quoted Prices in Active Markets for Identical Assets (Level 1)
Current co-promote termination liability
Sep. 30, 2014
Recurring
Quoted Prices in Active Markets for Identical Assets (Level 1)
Long-term contingent liabilities-Metabasis
Dec. 31, 2013
Recurring
Quoted Prices in Active Markets for Identical Assets (Level 1)
Long-term contingent liabilities-Metabasis
Sep. 30, 2014
Recurring
Quoted Prices in Active Markets for Identical Assets (Level 1)
Long-term contingent liabilities-CyDex
Dec. 31, 2013
Recurring
Quoted Prices in Active Markets for Identical Assets (Level 1)
Long-term contingent liabilities-CyDex
Sep. 30, 2014
Recurring
Quoted Prices in Active Markets for Identical Assets (Level 1)
Liability for short-term investments owed to former licensees
Dec. 31, 2013
Recurring
Quoted Prices in Active Markets for Identical Assets (Level 1)
Liability for short-term investments owed to former licensees
Dec. 31, 2013
Recurring
Quoted Prices in Active Markets for Identical Assets (Level 1)
Long-term portion of co-promote termination liability
Sep. 30, 2014
Recurring
Quoted Prices in Active Markets for Identical Assets (Level 1)
Current co-promote termination payments receivable
Dec. 31, 2013
Recurring
Quoted Prices in Active Markets for Identical Assets (Level 1)
Current co-promote termination payments receivable
Sep. 30, 2014
Recurring
Quoted Prices in Active Markets for Identical Assets (Level 1)
Available-for-sale securities
Dec. 31, 2013
Recurring
Quoted Prices in Active Markets for Identical Assets (Level 1)
Available-for-sale securities
Dec. 31, 2013
Recurring
Quoted Prices in Active Markets for Identical Assets (Level 1)
Long-term portion of co-promote termination payments receivable
Sep. 30, 2014
Recurring
Significant Other Observable Inputs (Level 2)
Dec. 31, 2013
Recurring
Significant Other Observable Inputs (Level 2)
Sep. 30, 2014
Recurring
Significant Other Observable Inputs (Level 2)
Current contingent liabilities-CyDex
Dec. 31, 2013
Recurring
Significant Other Observable Inputs (Level 2)
Current contingent liabilities-CyDex
Sep. 30, 2014
Recurring
Significant Other Observable Inputs (Level 2)
Current co-promote termination liability
Dec. 31, 2013
Recurring
Significant Other Observable Inputs (Level 2)
Current co-promote termination liability
Sep. 30, 2014
Recurring
Significant Other Observable Inputs (Level 2)
Long-term contingent liabilities-Metabasis
Dec. 31, 2013
Recurring
Significant Other Observable Inputs (Level 2)
Long-term contingent liabilities-Metabasis
Sep. 30, 2014
Recurring
Significant Other Observable Inputs (Level 2)
Long-term contingent liabilities-CyDex
Dec. 31, 2013
Recurring
Significant Other Observable Inputs (Level 2)
Long-term contingent liabilities-CyDex
Sep. 30, 2014
Recurring
Significant Other Observable Inputs (Level 2)
Liability for short-term investments owed to former licensees
Dec. 31, 2013
Recurring
Significant Other Observable Inputs (Level 2)
Liability for short-term investments owed to former licensees
Dec. 31, 2013
Recurring
Significant Other Observable Inputs (Level 2)
Long-term portion of co-promote termination liability
Sep. 30, 2014
Recurring
Significant Other Observable Inputs (Level 2)
Current co-promote termination payments receivable
Dec. 31, 2013
Recurring
Significant Other Observable Inputs (Level 2)
Current co-promote termination payments receivable
Sep. 30, 2014
Recurring
Significant Other Observable Inputs (Level 2)
Available-for-sale securities
Dec. 31, 2013
Recurring
Significant Other Observable Inputs (Level 2)
Available-for-sale securities
Dec. 31, 2013
Recurring
Significant Other Observable Inputs (Level 2)
Long-term portion of co-promote termination payments receivable
Sep. 30, 2014
Recurring
Significant Unobservable Inputs (Level 3)
Dec. 31, 2013
Recurring
Significant Unobservable Inputs (Level 3)
Sep. 30, 2014
Recurring
Significant Unobservable Inputs (Level 3)
Current contingent liabilities-CyDex
Dec. 31, 2013
Recurring
Significant Unobservable Inputs (Level 3)
Current contingent liabilities-CyDex
Sep. 30, 2014
Recurring
Significant Unobservable Inputs (Level 3)
Current co-promote termination liability
Dec. 31, 2013
Recurring
Significant Unobservable Inputs (Level 3)
Current co-promote termination liability
Sep. 30, 2014
Recurring
Significant Unobservable Inputs (Level 3)
Long-term contingent liabilities-Metabasis
Dec. 31, 2013
Recurring
Significant Unobservable Inputs (Level 3)
Long-term contingent liabilities-Metabasis
Sep. 30, 2014
Recurring
Significant Unobservable Inputs (Level 3)
Long-term contingent liabilities-CyDex
Dec. 31, 2013
Recurring
Significant Unobservable Inputs (Level 3)
Long-term contingent liabilities-CyDex
Sep. 30, 2014
Recurring
Significant Unobservable Inputs (Level 3)
Liability for short-term investments owed to former licensees
Dec. 31, 2013
Recurring
Significant Unobservable Inputs (Level 3)
Liability for short-term investments owed to former licensees
Dec. 31, 2013
Recurring
Significant Unobservable Inputs (Level 3)
Long-term portion of co-promote termination liability
Sep. 30, 2014
Recurring
Significant Unobservable Inputs (Level 3)
Current co-promote termination payments receivable
Dec. 31, 2013
Recurring
Significant Unobservable Inputs (Level 3)
Current co-promote termination payments receivable
Sep. 30, 2014
Recurring
Significant Unobservable Inputs (Level 3)
Available-for-sale securities
Dec. 31, 2013
Recurring
Significant Unobservable Inputs (Level 3)
Available-for-sale securities
Dec. 31, 2013
Recurring
Significant Unobservable Inputs (Level 3)
Long-term portion of co-promote termination payments receivable
Assets:                                                                                                                                                      
Assets, fair value       $ 6,448,000 $ 16,086,000                       $ 523,000 $ 4,329,000 $ 5,925,000 $ 4,340,000 $ 7,417,000 $ 5,925,000 $ 4,340,000                       $ 0 $ 0 $ 5,925,000 $ 4,340,000 $ 0 $ 0 $ 0                       $ 0 $ 0 $ 0 $ 0 $ 0 $ 523,000 $ 11,746,000                       $ 523,000 $ 4,329,000 $ 0 $ 0 $ 7,417,000
Liabilities:                                                                                                                                                      
Liabilities, fair value       17,890,000 25,904,000 4,184,000 1,712,000 523,000 4,329,000 3,511,000 4,196,000 8,755,000 7,599,000 917,000 651,000 7,417,000           4,428,000 4,847,000 0 0 0 0 3,511,000 4,196,000 0 0 917,000 651,000 0           0 0 0 0 0 0 0 0 0 0 0 0 0           13,462,000 21,057,000 4,184,000 1,712,000 523,000 4,329,000 0 0 8,755,000 7,599,000 0 0 7,417,000          
Principal amount outstanding 245,000,000 0 245,000,000                                                                                                                                                
Estimated fair value of debt $ 229,800,000