Income Taxes (Details) - USD ($) $ in Thousands	12 Months Ended
	Oct. 31, 2016	Oct. 31, 2015	Oct. 31, 2014
Operating Loss Carryforwards [Line Items]
Unrecognized Tax Benefits	$ 15,700	$ 15,700
Income (Loss) from Continuing Operations before Income Taxes, Domestic	(46,708)	(26,459)	$ (35,167)
Income (Loss) from Continuing Operations before Income Taxes, Foreign	(3,981)	(2,951)	(3,228)
Loss before provision for income taxes	(50,689)	(29,410)	(38,395)
Current Foreign Tax Expense (Benefit)	500	300	500
franchise tax expense	$ 400	$ 200	$ 200
Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate	(34.00%)	(34.00%)	(34.00%)
Effective Income Tax Rate Reconciliation, State and Local Income Taxes	(0.20%)	(0.10%)	(1.80%)
Effective Income Tax Rate Reconciliation, Foreign Income Tax Rate Differential	1.10%	0.90%	1.00%
effective income tax rate reconciliation, net operating loss adjustment	3.30%	4.70%	(25.40%)
Effective Income Tax Rate Reconciliation, Nondeductible Expense	0.90%	0.10%	14.50%
Effective Income Tax Rate Reconciliation, Change in Enacted Tax Rate	(0.30%)	1.60%	(0.80%)
Effective Income Tax Rate Reconciliation, Other Adjustments	0.20%	0.40%	0.40%
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance	30.10%	27.30%	47.10%
Effective Income Tax Rate, Continuing Operations	1.10%	0.90%	1.00%
Deferred Tax Assets, Grant Revenue	$ 1,327	$ 0
Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Employee Benefits	9,625	8,389
Deferred Tax Assets, Tax Deferred Expense, Reserves and Accruals, Allowance for Doubtful Accounts	1,276	1,109
Deferred Tax Assets, Capital Loss Carryforwards	12,772	12,998
Deferred Tax Assets, Operating Loss Carryforwards	265,799	257,373
deferred tax assets, deferred license revenue	8,616	9,313
Deferred Tax Assets, Inventory	278	77
Deferred Tax Assets, Property, Plant and Equipment	4,653	535
Deferred Tax Assets, Gross	304,346	289,794
Deferred Tax Assets, Valuation Allowance	(304,346)	(289,794)
Deferred Tax Assets, Net of Valuation Allowance	0	0
Deferred Tax Liabilities, Deferred Expense, Capitalized Research and Development Costs	(3,377)	(3,377)
Deferred Tax Liabilities, Net	3,377	$ 3,377
Federal Operating Loss Carryforwards	748,600
State Operating Loss Carryforwards	405,800
Tax Credits, State	11,100
Amount of Tax Credits to Expire	$ 700
Minimum [Member]
Operating Loss Carryforwards [Line Items]
Tax Credit Carryforward, Expiration Date	Jan. 01, 2017
Maximum [Member]
Operating Loss Carryforwards [Line Items]
Tax Credit Carryforward, Expiration Date	Jan. 01, 2035