Income Taxes (Tables)

12 Months Ended

Dec. 31, 2022

Income Tax Disclosure [Abstract]

Schedule of Income before Income Tax, Domestic and Foreign [Table Text Block]

Our Income (loss) before income taxes consisted of the following:

	Year Ended December 31,
(in millions)	2022		2021		2020
Domestic	$	(1,119)	$	(648)	$	(660)
Foreign	2,260		1,724		581
	$	1,141	$	1,076	$	(79)

Schedule of Components of Income Tax Expense (Benefit) [Table Text Block]

The related expense (benefit) for income taxes consisted of the following:

	Year Ended December 31,
(in millions)	2022		2021		2020
Current
Federal	$	51	$	18	$	(29)
State	19		33		(35)
Foreign	381		127		151
	451		178		87
Deferred
Federal	(92)		(256)		(26)
State	(32)		(3)		(6)
Foreign	117		117		(53)
	(7)		(142)		(85)
	$	443	$	36	$	2

Schedule of Deferred Tax Assets and Liabilities [Table Text Block]

Significant components of our deferred tax assets and liabilities are as follows:

	As of December 31,
(in millions)	2022		2021
Deferred Tax Assets:
Inventory costs and related reserves	$	19	$	10
Tax benefit of net operating losses and credits	511		620
Reserves and accruals	304		324
Restructuring-related charges	6		14
Litigation and product liability reserves	103		127
Investment write-down	38		31
Compensation related	136		130
Federal benefit of uncertain tax positions	9		8
Intangible assets	3,668		3,546
Capitalized R&D	160		67
Property, plant and equipment	2		14
Other	—		35
	4,954		4,926
Less: valuation allowance	(1,004)		(1,014)
	3,950		3,912
Deferred Tax Liabilities:
Unrealized gains and losses on derivative financial instruments	117		79
Other	34		—
	151		79
Net Deferred Tax Assets	3,799		3,833
Prepaid on intercompany profit	264		205
Net Deferred Tax Assets and Prepaid on Intercompany Profit	$	4,062	$	4,038

Our deferred tax assets, deferred tax liabilities and prepaid on intercompany profit are included in the following locations within our accompanying consolidated balance sheets (in millions):

	Location on Consolidated Balance Sheets	As of December 31,
Component		2022		2021
Prepaid on intercompany profit	Prepaid income taxes	$	264	$	205
Non-current deferred tax asset	Deferred tax assets	3,942		4,142
Deferred Tax Assets and Prepaid on Intercompany Profit		4,206		4,348
Non-current deferred tax liability	Deferred tax liabilities	144		310
Deferred Tax Liabilities		144		310
Net Deferred Tax Assets and Prepaid on Intercompany Profit		$	4,062	$	4,038

Summary of Income Tax Contingencies [Table Text Block]

A reconciliation of the beginning and ending amount of unrecognized tax benefits is as follows:

	Year Ended December 31,
(in millions)	2022		2021		2020
Beginning Balance	$	255	$	261	$	455
Additions based on positions related to the current year	88		8		28
Additions based on positions related to prior years	177		41		6
Reductions for tax positions of prior years	(20)		(36)		(186)
Settlements with taxing authorities	(1)		(2)		(27)
Statute of limitation expirations	(8)		(17)		(15)
Ending Balance	$	492	$	255	$	261

Tax rate

The reconciliation of income taxes at the federal statutory rate to the actual expense (benefit) for income taxes is as follows:

	Year Ended December 31,
	2022		2021		2020
U.S. federal statutory income tax rate	21.0	%	21.0	%	(21.0)	%
State income taxes, net of federal benefit	0.7	%	2.5	%	16.6	%
Domestic taxes on foreign earnings	15.3	%	6.8	%	155.4	%
Effect of foreign taxes	(3.8)	%	(14.3)	%	(40.7)	%
Acquisition-related	4.4	%	(8.1)	%	(16.7)	%
Research credit	(4.5)	%	(3.0)	%	(43.0)	%
Valuation allowance	(1.3)	%	0.8	%	(42.0)	%
Goodwill impairment charges	—	%	—	%	3.7	%
Compensation-related	0.6	%	(0.6)	%	(7.7)	%
Non-deductible expenses	0.4	%	0.4	%	64.4	%
Uncertain tax positions	7.7	%	1.2	%	(96.8)	%
Intra-entity asset transfers	—	%	—	%	10.2	%
Return to provision	(2.1)	%	(5.7)	%	(37.3)	%
Change in tax rates	(0.2)	%	1.9	%	51.8	%
Other, net	0.7	%	0.4	%	6.0	%
	38.9	%	3.3	%	2.9	%