Consolidated Statements of Operations - USD ($) shares in Thousands, $ in Millions	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Net sales	$ 12,682	$ 11,888	$ 9,913
Cost of products sold	3,956	3,711	3,465
Gross profit	8,727	8,177	6,448
Operating expenses:
Selling, general and administrative expenses	4,520	4,359	3,787
Research and development expenses	1,323	1,204	1,143
Royalty expense	47	49	45
Amortization expense	803	741	789
Goodwill impairment charges	0	0	73
Intangible asset impairment charges	132	370	460
Contingent consideration net expense (benefit)	35	(136)	(100)
Restructuring net charges (credits)	24	40	52
Litigation-related net charges (credits)	173	430	278
Gain (Loss) on Disposition of Assets	22	(78)	0
Operating expenses	7,078	6,978	6,528
Operating income (loss)	1,649	1,199	(80)
Other income (expense):
Interest expense	(470)	(341)	(361)
Other, net	(38)	218	362
Income (loss) before income taxes	1,141	1,076	(79)
Income tax expense (benefit)	443	36	2
Net income (loss)	698	1,041	(82)
Preferred stock dividends	55	55	33
Net income (loss) available to common stockholders	$ 642	$ 985	$ (115)
Net income (loss) per common share — basic	$ 0.45	$ 0.69	$ (0.08)
Net income (loss) per common share — assuming dilution	$ 0.45	$ 0.69	$ (0.08)
Weighted-average shares outstanding
Basic	1,430,500	1,422,300	1,416,700
Assuming dilution	1,439,700	1,433,800	1,416,700