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Supplemental Balance Sheet Information (Details) - USD ($)
$ in Millions
3 Months Ended 9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Sep. 30, 2022
Sep. 30, 2021
Dec. 31, 2021
Dec. 31, 2020
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents [Line Items]            
Cash and Cash Equivalents $ 338 $ 1,947 $ 338 $ 1,947 $ 1,925  
Restricted Cash and Cash Equivalents in Other current assets 112 155 112 155 188  
Restricted Cash Equivalents in Other long-term assets 48 57 48 57 55  
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents 497 2,159 497 2,159 2,168 $ 1,995
Depreciation 82 88 238 254    
Trade accounts receivable, net            
Accounts receivable 1,986   1,986   1,886  
Less: allowance for doubtful accounts (114)   (114)   (108)  
Trade accounts receivable, net 1,871   1,871   1,778  
Allowance for doubtful accounts            
Beginning balance 117 107 108 105    
Charges to expenses 7 9 26 20    
Utilization of allowances (9) (7) (20) (17)    
Ending balance 114 108 114 108    
Inventories            
Inventory, Finished Goods, Net of Reserves 1,107   1,107   1,029  
Inventory, Work in Process, Net of Reserves 149   149   128  
Inventory, Raw Materials, Net of Reserves 533   533   452  
Inventories 1,788   1,788   1,610  
Other Current Assets [Abstract]            
Restricted Cash and Cash Equivalents in Other current assets 112 155 112 155 188  
Derivative Asset, Current 367   367   226  
Licensing arrangements 73   73   132  
Other Assets, Miscellaneous, Current 332   332   254  
Other Assets, Current 884   884   799  
Property, plant and equipment, net            
Land 117   117   109  
Buildings and improvements 1,461   1,461   1,335  
Equipment, furniture and fixtures 3,372   3,372   3,475  
Capital in progress 513   513   605  
Property, plant and equipment 5,463   5,463   5,525  
Less: accumulated depreciation 3,190   3,190   3,273  
Property, plant and equipment, net 2,273   2,273   2,252  
Supplemental Balance Sheet Information            
Depreciation expense 82 88 238 254    
Other Assets, Noncurrent [Abstract]            
Restricted cash equivalents included in Other long-term assets 48 $ 57 48 $ 57 55  
Operating Lease, Right-of-Use Asset 388   388   435  
Derivative Asset 285   285   169  
Investments 389   389   412  
Licensing arrangements, asset 78   78   114  
Indemnification asset 168   168   0  
Other, Other Long-term Assets 247   247   225  
Other Assets, Noncurrent 1,602   1,602   1,410  
Accrued expenses            
Legal reserves, current 174   174   264  
Payroll and related liabilities 777   777   848  
Accrued Rebates, Current 341   341   350  
Business Combination, Contingent Consideration, Liability, Current 87   87   289  
Other 596   596   686  
Accrued Liabilities, Current 1,974   1,974   2,436  
Other Liabilities, Current [Abstract]            
Deferred Revenue, Current 216   216   208  
Accrued Royalties, Current 83   83   138  
Taxes Payable, Current 234   234   209  
Other Sundry Liabilities, Current 220   220   228  
Other Liabilities, Current 752   752   783  
Other long-term liabilities            
Accrued income taxes 549   549   442  
Estimated Litigation Liability, Noncurrent 130   130   284  
Business Combination, Contingent Consideration, Liability, Noncurrent 95   95   197  
Licensing arrangements, liability 84   84   143  
Operating Lease, Liability, Noncurrent 350   350   389  
Deferred Revenue 278   278   276  
Other Accrued Liabilities, Noncurrent 429   429   489  
Other long-term liabilities $ 1,916   $ 1,916   $ 2,220