Supplemental Balance Sheet Information (Details) - USD ($) $ in Millions	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021	Dec. 31, 2021	Dec. 31, 2020
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents [Line Items]
Cash and Cash Equivalents	$ 325	$ 2,016	$ 1,925
Restricted Cash and Cash Equivalents in Other current assets	146	184	188
Restricted Cash Equivalents in Other long-term assets	59	53	55
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents	529	2,253	2,168	$ 1,995
Trade accounts receivable, net
Accounts receivable	1,979		1,886
Less: allowance for doubtful accounts	(113)		(108)
Trade accounts receivable, net	1,866		1,778
Allowance for doubtful accounts
Beginning balance	108	105
Charges to expenses	11	2
Utilization of allowances	(5)	(6)
Ending balance	113	101
Inventories
Inventory, Finished Goods, Net of Reserves	1,095		1,029
Inventory, Work in Process, Net of Reserves	142		128
Inventory, Raw Materials, Net of Reserves	499		452
Inventories	1,736		1,610
Other Current Assets [Abstract]
Restricted Cash and Cash Equivalents in Other current assets	146	184	188
Derivative Asset, Current	266		226
Licensing arrangements	114		132
Other Assets, Miscellaneous, Current	363		254
Other Assets, Current	889		799
Property, plant and equipment, net
Land	120		109
Buildings and improvements	1,415		1,335
Equipment, furniture and fixtures	3,492		3,475
Capital in progress	539		605
Property, plant and equipment	5,565		5,525
Less: accumulated depreciation	3,300		3,273
Property, plant and equipment, net	2,265		2,252
Supplemental Balance Sheet Information
Depreciation expense	76	83
Other Assets, Noncurrent [Abstract]
Restricted cash equivalents included in Other long-term assets	59	$ 53	55
Operating Lease, Right-of-Use Asset	424		435
Derivative Asset	155		169
Investments	406		412
Licensing arrangements, asset	101		114
Other, Other Long-term Assets	230		225
Other Assets, Noncurrent	1,375		1,410
Accrued expenses
Legal reserves, current	279		264
Payroll and related liabilities	705		848
Accrued Rebates, Current	329		350
Business Combination, Contingent Consideration, Liability, Current	393		289
Other	601		686
Accrued Liabilities, Current	2,306		2,436
Other Liabilities, Current [Abstract]
Deferred Revenue, Current	212		208
Accrued Royalties, Current	122		138
Taxes Payable, Current	459		209
Other Sundry Liabilities, Current	241		228
Other Liabilities, Current	1,034		783
Other long-term liabilities
Accrued income taxes	451		442
Estimated Litigation Liability, Noncurrent	230		284
Business Combination, Contingent Consideration, Liability, Noncurrent	63		197
Licensing arrangements, liability	109		143
Operating Lease, Liability, Noncurrent	378		389
Deferred Revenue	279		276
Other Accrued Liabilities, Noncurrent	490		489
Other long-term liabilities	$ 2,000		$ 2,220