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Supplemental Balance Sheet Information (Tables)
 12 Months Ended
Dec. 31, 2021
Supplemental Balance Sheet Information [Abstract]  
Trade accounts receivable, net [Table Text Block]
Trade accounts receivable, net
 As of December 31,
(in millions)20212020
Trade accounts receivable$1,886 $1,637 
Allowance for credit losses(108)(105)
 $1,778 $1,531 

The following is a rollforward of our Allowance for credit losses:
Year Ended December 31,
(in millions)202120202019
Beginning balance$105 $74 $68 
Cumulative effect adjustment for adoption of ASU 2016-13n/a10 n/a
Credit loss expense28 49 23 
Write-offs(25)(27)(17)
Ending balance$108 $105 $74 
Note: Effective January 1, 2020, we adopted FASB ASC Topic 326 using the modified retrospective method, which requires that we recognize credit loss reserves when financial assets are established if credit losses are expected over the asset’s contractual life. Prior period amounts have not been restated and are presented in accordance with FASB ASC Topic 310.
Schedule of Inventory, Current Inventories
 As of December 31,
(in millions)20212020
Finished goods$1,029 $893 
Work-in-process128 109 
Raw materials452 349 
 $1,610 $1,351 
Schedule of Other Current Assets [Table Text Block] Other current assets
 As of December 31,
(in millions)20212020
Restricted cash and restricted cash equivalents$188 $208 
Derivative assets226 133 
Licensing arrangements132 148 
Other254 263 
 $799 $751 
Property, plant and equipment, net [Table Text Block] Property, plant and equipment, net
 As of December 31,
(in millions)20212020
Land$109 $104 
Buildings and improvements1,335 1,292 
Equipment, furniture and fixtures3,475 3,465 
Capital in progress605 446 
 5,525 5,308 
Less: accumulated depreciation3,273 3,224 
 $2,252 $2,084 
Schedule of Other Assets [Table Text Block] Other long-term assets
 As of December 31,
(in millions)20212020
Restricted cash equivalents$55 $52 
Operating lease right-of-use assets435 458 
Derivative assets169 109 
Investments412 918 
Licensing arrangements114 218 
Other225 166 
 $1,410 $1,921 
Schedule of Accrued Liabilities [Table Text Block] Accrued expenses
 As of December 31,
(in millions)20212020
Legal reserves$264 $505 
Payroll and related liabilities848 681 
Rebates350 331 
Contingent consideration289 26 
Other686 656 
 $2,436 $2,197 
Other Current Liabilities [Table Text Block] Other current liabilities
 As of December 31,
(in millions)20212020
Deferred revenue$208 $138 
Licensing arrangements138 153 
Taxes payable209 158 
Liabilities held for sale— 200 
Other228 307 
 $783 $958 
Other long-term liabilities [Table Text Block] Other long-term liabilities
 As of December 31,
(in millions)20212020
Accrued income taxes$442 $547 
Legal reserves284 64 
Contingent consideration197 171 
Licensing arrangements143 253 
Operating lease liabilities389 401 
Deferred revenue276 257 
Other489 615 
 $2,220 $2,309