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Hedging Activities and Fair Value Measurements (Tables)
 12 Months Ended
Dec. 31, 2021
Derivative [Line Items]  
Schedule of Notional Amounts of Outstanding Derivative Positions (Table Text Block) The following table presents the contractual amounts of our hedging instruments outstanding:
(in millions)FASB ASC Topic 815 DesignationAs of December 31,
20212020
Forward currency contractsCash flow hedge$3,996 $4,531 
Forward currency contractsNet investment hedge493 1,004 
Foreign currency-denominated debt(1)
Net investment hedge997 868 
Forward currency contractsNon-designated3,892 4,946 
Total Notional Outstanding$9,378 $11,349 
Derivative Instruments, Gain (Loss) [Table Text Block]
The following presents the effect of our derivative and nonderivative instruments designated as cash flow and net investment hedges under FASB ASC Topic 815 in our accompanying consolidated statements of operations. Refer to Note Q – Changes in Other Comprehensive Income for the total amounts relating to derivative and nonderivative instruments presented within our consolidated statements of comprehensive income (loss).
Effect of Hedging Relationships on Accumulated Other Comprehensive Income
Amount Recognized in OCI on Hedges
Consolidated Statements of Operations(1)
Amount Reclassified from AOCI into Earnings
(in millions)Pre-Tax Gain (Loss)Tax Benefit (Expense)Gain (Loss) Net of TaxLocation of Amount Reclassified and Total Amount of Line ItemPre-Tax (Gain) LossTax (Benefit) Expense(Gain) Loss Net of Tax
Year Ended December 31, 2021
Forward currency contracts
Cash flow hedges$268 $(60)$208 Cost of products sold$3,711 $(54)$12 $(42)
Net investment hedges(2)
56 (13)43 Interest expense341 (13)3 (10)
Foreign currency-denominated debt
Net investment hedges(3)
82 (19)64 Other, net(218)— — — 
Interest rate derivative contracts
Cash flow hedges— — — Interest expense341 5 (1)4 
Year Ended December 31, 2020
Forward currency contracts
Cash flow hedges$(99)$22 $(77)Cost of products sold$3,465 $(83)$19 $(64)
Net investment hedges(2)
(37)8 (29)Interest expense361 (24)5 (19)
Foreign currency-denominated debt
Net investment hedges(3)
(89)21 (68)Other, net(362)— — — 
Interest rate derivative contracts
Cash flow hedges— — — Interest expense361 5 (1)4 
Year Ended December 31, 2019
Forward currency contracts
Cash flow hedges$150 $(34)$117 Cost of products sold$3,116 $(73)$16 $(56)
Net investment hedges(2)
68 (15)53 Interest expense473 (43)10 (33)
Foreign currency-denominated debt
Net investment hedges(3)
(14)3 (11)Other, net(358)— — — 
Interest rate derivative contracts
Cash flow hedges— — — Interest expense473 3 (1)2 
(1)    In all periods presented in the table above, the pre-tax (gain) loss amounts reclassified from AOCI to earnings represent the effect of the hedging relationships on earnings.
(2)    For our outstanding forward currency contracts designated as net investment hedges, the net gain or loss reclassified from AOCI to earnings as a reduction of Interest expense represents the straight-line amortization of the excluded component as calculated at the date of designation. This initial value of the excluded component has been excluded from the assessment of effectiveness in accordance with FASB ASC Topic 815. In the current and prior period, we did not recognize any gains or losses on the components included in the assessment of hedge effectiveness in earnings.
(3)    For our outstanding euro-denominated debt principal designated as a net investment hedge, the change in fair value attributable to changes in the spot rate is recorded in the CTA component of OCI. No amounts were reclassified from AOCI to current period earnings.
Derivative Instruments, Gain (Loss) that may be Reclassified from AOCI to Earnings within Twelve Months [Table Text Block]
As of December 31, 2021, pre-tax net gains or losses for our derivative instruments designated, or previously designated, as cash flow and net investment hedges under FASB ASC Topic 815 that may be reclassified from AOCI to earnings within the next twelve months are presented below (in millions):
Designated Hedging InstrumentFASB ASC Topic 815 DesignationLocation on Consolidated Statements of OperationsAmount of Pre-Tax Gain (Loss) that may be Reclassified to Earnings
Forward currency contractsCash flow hedgeCost of products sold$127 
Forward currency contractsNet investment hedgeInterest expense3 
Interest rate derivative contractsCash flow hedgeInterest expense(5)
Derivatives Not Designated as Hedging Instruments (Table Text Block)
Net gains and losses on currency hedge contracts not designated as hedging instruments offset by net gains and losses from currency transaction exposures are presented below:
(in millions)Location on Consolidated Statements of OperationsYear Ended December 31,
202120202019
Net gain (loss) on currency hedge contractsOther, net$(16)$73 $(343)
Net gain (loss) on currency transaction exposuresOther, net(12)(105)(15)
Net currency exchange gain (loss)$(27)$(32)$(358)
Schedule of Derivative Instruments in Statement of Financial Position, Fair Value (Table Text Block) The following are the balances of our derivative and nonderivative assets and liabilities:
(in millions)
Location on Consolidated Balance Sheets(1)
As of December 31,
20212020
Derivative and Nonderivative Assets:   
Designated Hedging Instruments  
Forward currency contractsOther current assets$183 $53 
Forward currency contractsOther long-term assets169 109 
  352 162 
Non-Designated Hedging Instruments   
Forward currency contractsOther current assets42 79 
Total Derivative and Nonderivative Assets $394 $242 
Derivative and Nonderivative Liabilities:   
Designated Hedging Instruments  
Forward currency contractsOther current liabilities$32 $44 
Forward currency contractsOther long-term liabilities6 54 
Foreign currency-denominated debt(2)
Other long-term liabilities1,011 1,094 
  1,049 1,191 
Non-Designated Hedging Instruments   
Forward currency contractsOther current liabilities22 71 
Total Derivative and Nonderivative Liabilities$1,071 $1,262 
(1)We classify derivative and nonderivative assets and liabilities as current when the settlement date of the contract is one year or less.
(2)Foreign currency-denominated debt is the portion of the €900 million debt principal designated as a net investment hedge. A portion of this notional is subject to de-designation and re-designation based on changes in the underlying hedged item.
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]  
Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block]
Assets and liabilities measured at fair value on a recurring basis consist of the following:
As of
 December 31, 2021December 31, 2020
(in millions)Level 1Level 2Level 3TotalLevel 1Level 2Level 3Total
Assets        
Money market funds and time deposits$1,632 $— $— $1,632 $1,584 $— $— $1,584 
Publicly-held securities10 — — 10 414 — — 414 
Hedging instruments— 394 — 394 — 242 — 242 
Licensing arrangements— — 246 246 — — 365 365 
 $1,642 $394 $246 $2,282 $1,998 $242 $365 $2,605 
Liabilities        
Hedging instruments$— $1,071 $— $1,071 $— $1,262 $— $1,262 
Contingent consideration liability— — 486 486 — — 196 196 
Licensing arrangements— — 281 281 — — 407 407 
 $— $1,071 $767 $1,838 $— $1,262 $603 $1,865 
The recurring Level 3 fair value measurements of our licensing arrangements recognized in our consolidated balance sheets as of December 31, 2021 include the following significant unobservable inputs:
Licensing ArrangementsFair Value as of December 31, 2021Valuation TechniqueUnobservable InputRange
Weighted Average(1)
Financial Asset$246 millionDiscounted Cash FlowDiscount Rate15%15%
Projected Year of Payment2022-20252023
Financial Liability$281 millionDiscounted Cash FlowDiscount Rate12%-15%13%
Projected Year of Payment2022-20262024
(1)    Unobservable inputs relate to a single financial asset and liability. As such, unobservable inputs were not weighted by the relative fair value of the instruments. For projected year of payment, the amount represents the median of the inputs and is not a weighted average.

Changes in the fair value of our licensing arrangements' financial asset were as follows:
(in millions)
Balance as of December 31, 2019$518 
Proceeds from royalty rights(175)
Fair value adjustment (expense) benefit22 
Balance as of December 31, 2020$365 
Proceeds from royalty rights(163)
Fair value adjustment (expense) benefit44 
Balance as of December 31, 2021$246 

Changes in the fair value of our licensing arrangements' financial liability were as follows:
(in millions)
Balance as of December 31, 2019$571 
Payments for royalty rights(186)
Fair value adjustment expense (benefit)22 
Balance as of December 31, 2020$407 
Payments for royalty rights(166)
Fair value adjustment expense (benefit)41 
Balance as of December 31, 2021$281