INTANGIBLE ASSETS AND GOODWILL (Details 2) (USD $) In Thousands, unless otherwise specified	12 Months Ended
	Dec. 31, 2011	Dec. 31, 2010	Dec. 31, 2009
Amortization expense related to intangible assets recorded as follows:
Alliance and royalty revenue	$ 1,072	$ 1,072	$ 1,072
Cost of goods sold	8,103	8,103	8,103
Amortization expense	557,814	219,758	104,730
Total amortization of intangible assets	566,989	228,933	113,905
Estimated aggregate amortization expense
2012	799,318
2013	801,101
2014	791,634
2015	772,828
2016	$ 772,595