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INTANGIBLE ASSETS AND GOODWILL (Details 2) (USD $)
In Thousands
3 Months Ended9 Months Ended
Sep. 30, 2011
Sep. 30, 2010
Sep. 30, 2011
Sep. 30, 2010
Amortization expense related to intangible assets recorded as follows:    
Alliance and royalty revenue$ 268$ 268$ 804$ 804
Cost of goods sold2,0262,0266,0776,077
Amortization expense138,02735,499365,016102,098
Total amortization of intangible assets140,32137,793371,897108,979
Estimated aggregate amortization expense    
2011  504,586 
2012  558,287 
2013  555,724 
2014  547,238 
2015  $ 533,910