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CONSOLIDATED STATEMENTS OF CASH FLOWS (USD $)
In Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2011
Jun. 30, 2010
Jun. 30, 2011
Jun. 30, 2010
Cash Flows From Operating Activities        
Net income $ 56,360 $ 33,969 $ 62,842 $ 30,819
Adjustments to reconcile net income to net cash provided by operating activities:        
Depreciation and amortization 122,276 40,233 249,278 80,281
Amortization of deferred revenue (4,776) (4,776) (9,551) (9,551)
Amortization of discounts on long-term debt 1,945 2,837 4,587 5,638
Amortization of deferred financing costs 469 1,332 1,761 2,644
Share-based compensation 25,558 1,895 55,451 3,552
Tax benefits from stock options exercised (7,566)   (31,616)  
Deferred income taxes (18,724) 700 (38,497) 5,000
Acquired in-process research and development 2,000 10,242 4,000 61,245
Acquisition-related contingent consideration 1,752 0 2,138 0
Allowances for losses on accounts receivable and inventories 2,091 3,757 2,472 246
Acquisition accounting adjustment on inventory sold 16,262   46,171  
Non-cash cost of alliance revenue     30,686  
Payment of accrued legal settlements (400)   (16,400) (5,950)
Additions to accrued legal settlements     400  
Loss on extinguishment of debt 14,748   23,010  
Payment of accreted interest on repurchase of convertible debt (2,712)   (5,001)  
Gain on sale of marketable securities (21,316)   (21,316)  
Other 6,263 238 6,982 (129)
Changes in operating assets and liabilities:        
Accounts receivable 67,736 (11,432) (50,745) 3,404
Inventories (8,217) 5,314 5,143 (5,810)
Prepaid expenses and other current assets 12,497 2,961 5,627 5,236
Accounts payable 27,497 (566) (10,309) (30,296)
Accrued liabilities (51,814) 17,803 10,928 3,000
Income taxes payable (13,730) 3,676 (14,593) 5,077
Deferred revenue (1,543) 730 (462) (740)
Net cash provided by operating activities 226,656 108,913 312,986 153,666
Cash Flows From Investing Activities        
Acquisition of businesses, net of cash acquired (96,565)   (560,267)  
Acquisition of intangible assets (8,000) (10,242) (310,885) (60,245)
Proceeds from sales and maturities of marketable securities 83,865 3,750 86,639 4,965
Purchases of marketable securities (29,326)   (69,342)  
Purchases of property, plant and equipment (12,474) (2,860) (33,979) (6,494)
Proceeds from sale of assets       8,542
Net cash used in investing activities (62,500) (9,352) (887,834) (53,232)
Cash Flows From Financing Activities        
Issuance of long-term debt     2,139,688  
Repayment of long-term debt   (12,500) (975,000) (12,500)
Repurchase of common shares (224,814)   (499,564)  
Repurchase of convertible debt (199,788)   (339,013)  
Borrowings under credit facilities 100,000   100,000  
Payment of employee withholding tax upon vesting of share-based awards (15,200)   (54,678)  
Tax benefits from stock options exercised 7,566   31,616  
Proceeds from exercise of stock options 6,133 1,254 29,362 2,798
Financing costs paid (4,066)   (19,813)  
Cash dividends paid 0 (14,256)   (28,502)
Net cash provided by (used in) financing activities (330,169) (25,502) 412,598 (38,204)
Effect of exchange rate changes on cash and cash equivalents 3,206 (385) 6,926 (127)
Net increase (decrease) in cash and cash equivalents (162,807) 73,674 (155,324) 62,103
Cash and cash equivalents, beginning of period 401,752 102,892 394,269 114,463
Cash and cash equivalents, end of period 238,945 176,566 238,945 176,566
Non-Cash Investing and Financing Activities        
Acquisition of businesses, contingent consideration at fair value (369,679)   (397,150)  
Settlement of convertible debt, equity issued (892,000)   (892,000)  
Cash dividends declared but unpaid   $ (15,064)   $ (15,064)