INTANGIBLE ASSETS AND GOODWILL (Details 2) (USD $) In Thousands, unless otherwise specified	12 Months Ended
	Dec. 31, 2012	Dec. 31, 2011	Dec. 31, 2010
Amortization expense related to intangible assets recorded as follows:
Alliance and royalty revenue		$ 1,072	$ 1,072
Cost of goods sold	2,557	8,103	8,103
Amortization expense	928,885	557,814	219,758
Total amortization of intangible assets	931,442	566,989	228,933
Estimated aggregate amortization expense
2013	1,050,614
2014	1,035,678
2015	1,015,956
2016	980,340
2017	$ 934,136