-----BEGIN PRIVACY-ENHANCED MESSAGE----- Proc-Type: 2001,MIC-CLEAR Originator-Name: webmaster@www.sec.gov Originator-Key-Asymmetric: MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB MIC-Info: RSA-MD5,RSA, MFkUpHEN3IHz1SzBXSUhu0N5ToWj5yCLbO3rLPXfi2kx/bofmtaoDdYDBs1Tu8kO rUwKP0GB/GqHma+vEEgTyw== 0000899140-01-000181.txt : 20010328 0000899140-01-000181.hdr.sgml : 20010328 ACCESSION NUMBER: 0000899140-01-000181 CONFORMED SUBMISSION TYPE: SC 13D/A PUBLIC DOCUMENT COUNT: 1 FILED AS OF DATE: 20010327 GROUP MEMBERS: E.M. WARBURG, PINCUS & CO., LLC GROUP MEMBERS: WARBURG PINCUS EQUITY PARTNERS LP GROUP MEMBERS: WARBURG, PINCUS & CO. GROUP MEMBERS: WARBURG, PINCUS EQUITY PARTNERS, L.P. SUBJECT COMPANY: COMPANY DATA: COMPANY CONFORMED NAME: TRANSKARYOTIC THERAPIES INC CENTRAL INDEX KEY: 0000885259 STANDARD INDUSTRIAL CLASSIFICATION: BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836] IRS NUMBER: 043027191 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: SC 13D/A SEC ACT: SEC FILE NUMBER: 005-47221 FILM NUMBER: 1580717 BUSINESS ADDRESS: STREET 1: 195 ALBANY ST CITY: CAMBRIDGE STATE: MA ZIP: 02139 BUSINESS PHONE: 6173490200 FILED BY: COMPANY DATA: COMPANY CONFORMED NAME: WARBURG PINCUS EQUITY PARTNERS LP CENTRAL INDEX KEY: 0001075598 STANDARD INDUSTRIAL CLASSIFICATION: [] FILING VALUES: FORM TYPE: SC 13D/A BUSINESS ADDRESS: STREET 1: 466 LEXINGTON AVE. CITY: NEW YORK STATE: NY ZIP: 10017 BUSINESS PHONE: 2128780600 SC 13D/A 1 0001.txt AMENDMENT NO. 2 TO SCHEDULE 13D -------------------------- OMB APPROVAL UNITED STATES -------------------------- SECURITIES AND EXCHANGE COMMISSION OMB Number: 3235-0145 Washington, D.C. 20549 Expires: October 31, 2002 Estimated average burden hours per response...14.9 -------------------------- SCHEDULE 13D (Amendment No. 2) Under the Securities Exchange Act of 1934* TRANSKARYOTIC THERAPIES, INC. - -------------------------------------------------------------------------------- (Name of Issuer) Common Stock, $0.01 Par Value - -------------------------------------------------------------------------------- (Title of Class of Securities) 893735 10 0 - -------------------------------------------------------------------------------- (CUSIP Number) Scott A. Arenare, Esq. Vice President and General Counsel E.M. Warburg, Pincus & Co., LLC 466 Lexington Avenue New York, New York 10017 (212) 878-0600 - -------------------------------------------------------------------------------- (Name, Address and Telephone Number of Person Authorized to Receive Notices and Communications) Copies to: Peter H. Jakes, Esq. Willkie Farr & Gallagher 787 Seventh Avenue New York, NY 10019-6099 (212) 728-8000 March 22, 2001 - -------------------------------------------------------------------------------- (Date of Event which Requires Filing of this Statement) If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of ss. 240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the following box: [ ] NOTE: Schedules filed in paper format shall include a signed original and five copies of the schedule, including all exhibits. See Rule 240.13d-7 for other parties to whom copies are to be sent. * The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page. The information required on the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes). Page 1 of 13 pages SCHEDULE 13D - --------------------- ------------------ CUSIP No. 893735 10 0 Page 2 of 13 Pages - --------------------- ------------------ - ----------- -------------------------------------------------------------------- 1 NAMES OF REPORTING PERSONS I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (entities only) Warburg, Pincus Equity Partners, L.P. I.R.S. #13-3986317 - ----------- -------------------------------------------------------------------- 2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions) (a) [X] (b) [ ] - ----------- -------------------------------------------------------------------- 3 SEC USE ONLY - ----------- -------------------------------------------------------------------- 4 SOURCE OF FUNDS (See Instructions) WC (See Item 3 for description of consideration) - ----------- -------------------------------------------------------------------- 5 CHECK IF DISCLOSURE OF LEGAL PROCEEDING IS REQUIRED PURSUANT TO ITEMS 2(d) or 2(e) [ ] - ----------- -------------------------------------------------------------------- 6 CITIZENSHIP OR PLACE OF ORGANIZATION Delaware - --------------------- --------- ------------------------------------------------ 7 SOLE VOTING POWER 4,724,742 --------- ------------------------------------------------ NUMBER OF 8 SHARED VOTING POWER SHARES BENEFICIALLY 0 OWNED BY EACH REPORTING --------- ------------------------------------------------ PERSON WITH 9 SOLE DISPOSITIVE POWER 4,724,742 --------- ------------------------------------------------ 10 SHARED DISPOSITIVE POWER 0 - ----------- -------------------------------------------------------------------- 11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 4,724,742 - ----------- -------------------------------------------------------------------- 12 CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES (See Instructions) [ ] - ----------- -------------------------------------------------------------------- 13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11) 18.0% - ----------- -------------------------------------------------------------------- 14 TYPE OF REPORTING PERSON (See Instructions) PN - ----------- -------------------------------------------------------------------- SCHEDULE 13D - ---------------------- ------------------ CUSIP No. 893735 10 0 Page 3 of 13 Pages - ---------------------- ------------------ - ----------- -------------------------------------------------------------------- 1 NAMES OF REPORTING PERSONS I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (entities only) Warburg, Pincus & Co. I.R.S. #13-6358475 - ----------- -------------------------------------------------------------------- 2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions) (a) [X] (b) [ ] - ----------- -------------------------------------------------------------------- 3 SEC USE ONLY - ----------- -------------------------------------------------------------------- 4 SOURCE OF FUNDS (See Instructions) WC (See Item 3 for description of consideration) - ----------- -------------------------------------------------------------------- 5 CHECK IF DISCLOSURE OF LEGAL PROCEEDING IS REQUIRED PURSUANT TO ITEMS 2(d) or 2(e) [ ] - ----------- -------------------------------------------------------------------- 6 CITIZENSHIP OR PLACE OF ORGANIZATION New York - --------------------- --------- ------------------------------------------------ 7 SOLE VOTING POWER 38,657 --------- ------------------------------------------------ NUMBER OF 8 SHARED VOTING POWER SHARES BENEFICIALLY 4,999,728 OWNED BY EACH REPORTING --------- ------------------------------------------------ PERSON WITH 9 SOLE DISPOSITIVE POWER 38,657 --------- ------------------------------------------------ 10 SHARED DISPOSITIVE POWER 4,999,728 - ----------- -------------------------------------------------------------------- 11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 5,038,385 - ----------- -------------------------------------------------------------------- 12 CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES (See Instructions) [ ] - ----------- -------------------------------------------------------------------- 13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11) 19.2% - ----------- -------------------------------------------------------------------- 14 TYPE OF REPORTING PERSON (See Instructions) PN - ----------- -------------------------------------------------------------------- SCHEDULE 13D - -------------------------- ------------------------ CUSIP No. 893735 10 0 Page 4 of 13 Pages - -------------------------- ------------------------ - ----------- -------------------------------------------------------------------- 1 NAMES OF REPORTING PERSONS I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (entities only) E.M. Warburg, Pincus & Co., LLC I.R.S. #13-3536050 - ----------- -------------------------------------------------------------------- 2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions) (a) [X] (b) [ ] - ----------- -------------------------------------------------------------------- 3 SEC USE ONLY - ----------- -------------------------------------------------------------------- 4 SOURCE OF FUNDS (See Instructions) WC (See Item 3 for description of consideration) - ----------- -------------------------------------------------------------------- 5 CHECK IF DISCLOSURE OF LEGAL PROCEEDING IS REQUIRED PURSUANT TO ITEMS 2(d) or 2(e) [ ] - ----------- -------------------------------------------------------------------- 6 CITIZENSHIP OR PLACE OF ORGANIZATION New York - --------------------- --------- ------------------------------------------------ 7 SOLE VOTING POWER 0 --------- ------------------------------------------------ NUMBER OF 8 SHARED VOTING POWER SHARES BENEFICIALLY 4,999,728 OWNED BY EACH REPORTING --------- ------------------------------------------------ PERSON WITH 9 SOLE DISPOSITIVE POWER 0 --------- ------------------------------------------------ 10 SHARED DISPOSITIVE POWER 4,999,728 - ----------- -------------------------------------------------------------------- 11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 4,999,728 - ----------- -------------------------------------------------------------------- 12 CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES (See Instructions) [ ] - ----------- -------------------------------------------------------------------- 13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11) 19.0% - ----------- -------------------------------------------------------------------- 14 TYPE OF REPORTING PERSON (See Instructions) OO - ----------- -------------------------------------------------------------------- This Amendment No. 2 (the "Amendment") amends the Schedule 13D filed on June 16, 2000, as amended by an Amendment No. 1 filed on June 29, 2000 (such Schedule 13D, as so amended, the "Schedule 13D") and is being filed on behalf of Warburg, Pincus Equity Partners, L.P., a Delaware limited partnership ("WPEP"), Warburg, Pincus & Co., a New York general partnership ("WP"), and E.M. Warburg, Pincus & Co., LLC, a New York limited liability company ("EMW" and, together with WPEP and WP, the "Reporting Entities"). This Amendment and the Schedule 13D relate to the Common Stock, par value $0.01, of Transkaryotic Therapies, Inc., a Delaware corporation (the "Company"). Unless the context otherwise requires, references herein and in the Schedule 13D to the "Common Stock" refer to the Common Stock of the Company, par value $0.01 per share. The holdings of Common Stock of WP and EMW in this Schedule 13D include certain shares of Common Stock that may be deemed to be beneficially owned by Warburg, Pincus Netherlands Equity Partners I, C.V. ("WPNEPI"), Warburg, Pincus Netherlands Equity Partners II, C.V. ("WPNEPII") and Warburg, Pincus Netherlands Equity Partners III, C.V. ("WPNEPIII" and, together with WPNEPI, WPNEPII and WPEP, the "Investors"). Unless otherwise indicated herein, each capitalized term used but not defined herein shall have the meaning assigned to such term in the Schedule 13D. This Amendment relates to the Common Stock and is being filed promptly following the acquisition of an aggregate of an additional 1,428,300 shares of Common Stock acquired by the Reporting Entities through various open market purchases (which purchases together represent more than 1.0% of the outstanding shares of Common Stock). Page 5 of 13 pages Item 2. Identity and Background. (a) Schedule I to Item 2(a) of the Schedule 13D is hereby amended in its entirety and is replaced with Schedule I attached hereto. Item 3. Source and Amount of Funds or Other Consideration. Item 3 of the Schedule 13D is hereby amended in its entirety to read as follows: "The total amount of funds used by the Reporting Entities to purchase the securities of the Company described herein was obtained from the working capital of the Reporting Entities and amounted to US $123,288,808 as of March 23, 2001." Item 5. Interest in Securities of the Issuer. Item 5 of the Schedule 13D is hereby amended in its entirety to read as follows: "(a) The Reporting Entities beneficially own shares of Common Stock by virtue of their ownership of shares of Common Stock directly as well as by their ownership of 3,571,428 of the Company's Series A Convertible Preferred Shares, each of which is convertible within sixty days into one share of Common Stock. As of March 23, 2001, WP beneficially owned 5,038,385 shares of Common Stock. Also as of this date, EMW beneficially owned 4,999,728 shares of Common Stock and WPEP beneficially owned 4,724,742 shares of Common Stock. Of the shares beneficially owned by WP and EMW, 274,985 shares represent the aggregate amount of Common Stock beneficially owned by the Investors. By reason of WP's and EMW's respective relationships with the Investors, under Rule 13d-3 under the Exchange Act, WP and EMW may be deemed to Page 6 of 13 pages own beneficially all of the shares of Common Stock that are beneficially owned by the Investors. Assuming full conversion of the corresponding Series A Convertible Preferred Shares, as of March 23 2001, the 5,038,385 shares of Common Stock beneficially held by WP, the 4,999,728 shares of Common Stock beneficially held by EMW and the 4,724,742 shares of Common Stock beneficially held by WPEP represented, respectively, approximately 19.2%, 19.0% and 18.0% of the sum of the 22,694,439 outstanding shares of Common Stock (based on the shares of Common Stock outstanding as of September 30, 2000, as set forth in the Company's most recent Quarterly Report on Form 10-Q, for the period ended September 30, 2000) and the 3,571,428 shares of Common Stock issuable upon conversion of the Series A Preferred Shares held by the Reporting Entities. (b) WPEP has the sole power to vote or to direct the vote and to dispose or to direct the disposition with respect to the 4,724,742 shares of Common Stock beneficially owned by WPEP. In addition to having the sole power to vote or to direct the vote and to dispose or to direct the disposition with respect to the 38,657 shares of Common Stock it beneficially owns directly, WP may be deemed to have the shared power to vote or to direct the vote and to dispose or to direct the disposition by virtue of its ownership positions in WPEP and the Investors with respect to the 4,724,742 shares of Common Stock beneficially owned by WPEP and the aggregate of 274,985 shares of Common Stock beneficially owned by the Investors. Considering WP's direct and indirect beneficial ownership interests together, WP has an aggregate beneficial ownership interest of 5,038,385 shares of Common Stock. By virtue of its control positions in WPEP and the Investors, EMW may be deemed to have the shared power to vote or to Page 7 of 13 pages direct the vote and to dispose or to direct the disposition with respect to the 4,724,742 shares of Common Stock beneficially owned by WPEP and the aggregate of 274,985 shares of Common Stock beneficially owned by the Investors, resulting in EMW having an aggregate beneficial ownership interest of 4,999,728 shares of Common Stock. (c) Since the last filing of a Schedule 13D by the Reporting Entities relating to the Company's securities, WPEP acquired shares of the Common Stock through various open market purchases conducted in February and March 2001 at various prices, each of which such purchases was for less than 1.0% of the outstanding Common Stock but all of which such purchases together were for more than 1.0% of the outstanding Common Stock. All of the funds used by the Reporting Entities to effect these purchases came from the working capital of the Reporting Entities. The dates on which the purchases occurred and the prices at which the purchases were made are set forth in the table below: Date of Purchase Number of Shares Price per Share - ---------------- ---------------- --------------- February 2, 2001 872,500 $16.50 February 27, 2001 75,000 $17.13 March 1, 2001 20,000 $16.20 March 2, 2001 25,000 $16.25 March 5, 2001 50,000 $16.67 March 6, 2001 35,000 $16.23 March 7, 2001 35,000 $16.23 March 9, 2001 40,000 $15.85 March 12, 2001 40,000 $15.75 March 20, 2001 88,800 $14.97 March 20, 2001 47,000 $14.48 March 22, 2001 100,000 $13.94 Page 8 of 13 pages (d) Except as set forth in this Item 5, no person other than each respective record owner referred to herein of securities is known to have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, such securities. (e) Not applicable." Page 9 of 13 pages SIGNATURES After reasonable inquiry and to the best of our knowledge and belief, the undersigned certify that the information set forth in this statement is true, complete and correct. Dated: March 26, 2001 WARBURG, PINCUS EQUITY PARTNERS, L.P. By: Warburg, Pincus & Co., General Partner By: /s/ Reuben S. Leibowitz ---------------------------------- Name: Reuben S. Leibowitz Title: Partner Dated: March 26, 2001 WARBURG, PINCUS & CO. By: /s/ Reuben S. Leibowitz ---------------------------------- Name: Reuben S. Leibowitz Title: Partner Dated: March 26, 2001 E.M. WARBURG, PINCUS & CO., LLC By: /s/ Reuben S. Leibowitz ---------------------------------- Name: Reuben S. Leibowitz Title: Member Page 10 of 13 pages SCHEDULE I Set forth below is the name, position and present principal occupation of each of the general partners of Warburg, Pincus & Co. ("WP") and members of E.M. Warburg, Pincus & Co., LLC ("EMW"). The sole general partner of Warburg, Pincus Equity Partners, L.P. ("WPEP") is WP. WPEP, WP, and EMW are hereinafter collectively referred to as the "Reporting Entities". Except as otherwise indicated, the business address of each of such persons is 466 Lexington Avenue, New York, New York 10017, and each of such persons is a citizen of the United States. GENERAL PARTNERS OF WP ---------------------- - ------------------------- ------------------------------------------------------ PRESENT PRINCIPAL OCCUPATION IN ADDITION TO POSITION WITH WP, AND POSITIONS NAME WITH THE REPORTING ENTITIES - ------------------------- ------------------------------------------------------ Joel Ackerman Partner of WP; Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ Gregory Back Partner of WP; Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ David Barr Partner of WP; Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ Harold Brown Partner of WP; Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ Sean D. Carney Partner of WP; Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ Timothy J. Curt Partner of WP; Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ W. Bowman Cutter Partner of WP; Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ Cary J. Davis Partner of WP; Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ Stephen Distler Partner of WP; Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ Stewart K. P. Gross Partner of WP; Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ Patrick T. Hackett Partner of WP; Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ Jeffrey A. Harris Partner of WP; Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ William H. Janeway Partner of WP; Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ Charles R. Kaye Partner of WP; Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ Henry Kressel Partner of WP; Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ Joseph P. Landy Partner of WP; Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ Sidney Lapidus Partner of WP; Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ Kewsong Lee Partner of WP; Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ Jonathan S. Leff Partner of WP; Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ Reuben S. Leibowitz Partner of WP; Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ David E. Libowitz Partner of WP; Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ Nancy Martin Partner of WP; Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ Edward J. McKinley Partner of WP; Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ Rodman W. Moorhead III Partner of WP; Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ James Neary Partner of WP; Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ Howard H. Newman Partner of WP; Member and Vice Chairman of EMW - ------------------------- ------------------------------------------------------ Gary D. Nusbaum Partner of WP; Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ Dalip Pathak Partner of WP; Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ Lionel I. Pincus Managing Partner of WP; Managing Member, Chairman of the Board and Chief Executive Officer of EMW - ------------------------- ------------------------------------------------------ John D. Santoleri Partner of WP; Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ Steven G. Schneider Partner of WP; Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ Barry Taylor Partner of WP; Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ John L. Vogelstein Partner of WP; Member, and President of EMW - ------------------------- ------------------------------------------------------ Elizabeth H. Weatherman Partner of WP; Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ David Wenstrup Partner of WP; Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ Pincus & Co.* - ------------------------- ------------------------------------------------------ NL & Co.** - ------------------------- ------------------------------------------------------ - --------------------- * New York limited partnership; primary activity is ownership interest in WP and EMW. ** New York limited partnership; primary activity is ownership interest in WP. Page 11 of 13 pages MEMBERS OF EMW - ------------------------- ------------------------------------------------------ PRESENT PRINCIPAL OCCUPATION IN ADDITION TO POSITION WITH EMW LLC, AND POSITIONS NAME WITH THE REPORTING ENTITIES - ------------------------- ------------------------------------------------------ Joel Ackerman Member and Managing Director of EMW; Partner of WP - ------------------------- ------------------------------------------------------ Gregory Back Member and Managing Director of EMW; Partner of WP - ------------------------- ------------------------------------------------------ David Barr Member and Managing Director of EMW; Partner of WP - ------------------------- ------------------------------------------------------ Frank M. Brochin (1) Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ Harold Brown Member and Managing Director of EMW; Partner of WP - ------------------------- ------------------------------------------------------ Sean D. Carney Member and Managing Director of EMW; Partner of WP - ------------------------- ------------------------------------------------------ Timothy J. Curt Member and Managing Director of EMW; Partner of WP - ------------------------- ------------------------------------------------------ W. Bowman Cutter Member and Managing Director of EMW; Partner of WP - ------------------------- ------------------------------------------------------ Cary J. Davis Member and Managing Director of EMW; Partner of WP - ------------------------- ------------------------------------------------------ Stephen Distler Member and Managing Director of EMW; Partner of WP - ------------------------- ------------------------------------------------------ Tetsuya Fukagawa (2) Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ Makoto Fukuhara (2) Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ Stewart K. P. Gross Member and Managing Director of EMW; Partner of WP - ------------------------- ------------------------------------------------------ Alf Grunwald (3) Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ Patrick T. Hackett Member and Managing Director of EMW; Partner of WP - ------------------------- ------------------------------------------------------ Jeffrey A. Harris Member and Managing Director of EMW; Partner of WP - ------------------------- ------------------------------------------------------ Sung-Jin Hwang (4) Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ Roberto Italia (5) Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ William H. Janeway Member and Managing Director of EMW; Partner of WP - ------------------------- ------------------------------------------------------ Charles R. Kaye Member and Managing Director of EMW; Partner of WP - ------------------------- ------------------------------------------------------ Rajesh Khanna (6) Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ Henry Kressel Member and Managing Director of EMW; Partner of WP - ------------------------- ------------------------------------------------------ Rajiv B. Lall (6) Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ Joseph P. Landy Member and Managing Director of EMW; Partner of WP - ------------------------- ------------------------------------------------------ Sidney Lapidus Member and Managing Director of EMW; Partner of WP - ------------------------- ------------------------------------------------------ Kewsong Lee Member and Managing Director of EMW; Partner of WP - ------------------------- ------------------------------------------------------ Jonathan S. Leff Member and Managing Director of EMW; Partner of WP - ------------------------- ------------------------------------------------------ Reuben S. Leibowitz Member and Managing Director of EMW; Partner of WP - ------------------------- ------------------------------------------------------ David E. Libowitz Member and Managing Director of EMW; Partner of WP - ------------------------- ------------------------------------------------------ Nicholas J. Lowcock (7) Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ John W. MacIntosh (8) Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ Nancy Martin Member and Managing Director of EMW; Partner of WP - ------------------------- ------------------------------------------------------ Edward J. McKinley Member and Managing Director of EMW; Partner of WP - ------------------------- ------------------------------------------------------ Rodman W. Moorhead III Member and Managing Director of EMW; Partner of WP - ------------------------- ------------------------------------------------------ James Neary Member and Managing Director of EMW; Partner of WP - ------------------------- ------------------------------------------------------ Howard H. Newman Member and Managing Director of EMW; Partner of WP - ------------------------- ------------------------------------------------------ Gary D. Nusbaum Member and Managing Director of EMW; Partner of WP - ------------------------- ------------------------------------------------------ Dalip Pathak Member and Managing Director of EMW; Partner of WP - ------------------------- ------------------------------------------------------ Lionel I. Pincus Managing Member, Chairman of the Board and Chief Executive Officer of EMW; Managing Partner of WP - ------------------------- ------------------------------------------------------ Pulak Chandan Prasad (6) Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ John D. Santoleri Member and Managing Director of EMW; Partner of WP - ------------------------- ------------------------------------------------------ Page 12 of 13 pages MEMBERS OF EMW (continued) - ------------------------- ------------------------------------------------------ PRESENT PRINCIPAL OCCUPATION IN ADDITION TO POSITION WITH EMW, AND POSITIONS NAME WITH THE REPORTING ENTITIES - ------------------------- ------------------------------------------------------ Steven G. Schneider Member and Managing Director of EMW; Partner of WP - ------------------------- ------------------------------------------------------ Melchior Stahl (3) Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ Chang Q. Sun (9) Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ Barry Taylor Member and Managing Director of EMW, Partner of WP - ------------------------- ------------------------------------------------------ John L. Vogelstein Member and President of EMW; Partner of WP - ------------------------- ------------------------------------------------------ Elizabeth H. Weatherman Member and Managing Director of EMW; Partner of WP - ------------------------- ------------------------------------------------------ David Wenstrup Member and Managing Director of EMW; Partner of WP - ------------------------- ------------------------------------------------------ Jeremy S. Young (7) Member and Managing Director of EMW - ------------------------- ------------------------------------------------------ Pincus & Co.* - ------------------------- ------------------------------------------------------ (1) Citizen of France (2) Citizen of Japan (3) Citizen of Germany (4) Citizen of Korea (5) Citizen of Italy (6) Citizen of India (7) Citizen of United Kingdom (8) Citizen of Canada (9) Citizen of China * New York limited partnership; primary activity is ownership interest in WP and EMW Page 13 of 13 pages -----END PRIVACY-ENHANCED MESSAGE-----