CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2015	Sep. 30, 2014
Cash flows from operating activities:
Net loss	$ (171,285)	$ (156,851)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation, amortization and impairment charges	9,019	6,079
Stock-based compensation	29,009	24,583
Deferred executive compensation expense		119
Non-cash accrued interest	1,121
Deferred income tax benefit	(6,086)
Increase (decrease) from:
Accounts receivable	(7,078)	(5,957)
Inventory	(539)	1,549
Other assets	8,720	(1,558)
Accounts payable and other	13,901	1,292
Deferred revenue	2,560	1,445
Deferred executive compensation paid		(2,631)
Net cash used in operating activities	(120,658)	(131,930)
Cash flows from investing activities:
Investment in property and equipment	(4,446)	(2,475)
Net cash used in investing activities	(4,446)	(2,475)
Cash flows from financing activities:
Proceeds from royalty financing	50,000
Proceeds from issuance of convertible debt		192,921
Proceeds from issuance of warrants		27,580
Purchase of convertible bond hedges		(43,220)
Repayment of long-term debt	(313)	(9,100)
Reimbursement of amounts related to facility lease obligation	1,816
Proceeds from issuance of common stock pursuant to stock option and purchase plans	3,596	3,059
Payment of tax withholding obligations related to stock compensation	(321)	(716)
Net cash provided by financing activities	54,778	170,524
Effect of exchange rates on cash	(175)	153
Net increase (decrease) in cash and cash equivalents	(70,501)	36,272
Cash and cash equivalents, beginning of period	352,688	237,179
Cash and cash equivalents, end of period	282,187	273,451
Supplemental non-cash investing and financing disclosure:
Capitalization of construction-in-progress related to facility lease obligation	26,634	71,818
Investment in property and equipment included in accounts payable or accruals	1,106	$ 187
Deferred financing costs included in accounts payable or accruals	$ 3,846