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CONSOLIDATED STATEMENTS OF CASH FLOWS (USD $)
In Thousands, unless otherwise specified
12 Months Ended
Dec. 31, 2014
Dec. 31, 2013
Dec. 31, 2012
Cash flows from operating activities:      
Net loss $ (162,602)us-gaap_NetIncomeLoss $ (274,158)us-gaap_NetIncomeLoss $ (220,872)us-gaap_NetIncomeLoss
Adjustments to reconcile net loss to net cash used in operating activities:      
Depreciation, amortization and impairment charges 8,814aria_DepreciationAmortizationAndImpairmentCharges 4,136aria_DepreciationAmortizationAndImpairmentCharges 8,307aria_DepreciationAmortizationAndImpairmentCharges
Stock-based compensation 32,403us-gaap_ShareBasedCompensation 35,421us-gaap_ShareBasedCompensation 20,341us-gaap_ShareBasedCompensation
Deferred executive compensation expense 119us-gaap_DeferredCompensationArrangementWithIndividualCompensationExpense 963us-gaap_DeferredCompensationArrangementWithIndividualCompensationExpense 2,810us-gaap_DeferredCompensationArrangementWithIndividualCompensationExpense
Gain on disposition of stock (4,768)aria_GainLossOnDispositionOfStock    
Revaluation of warrant liability     15,924us-gaap_GainLossOnDerivativeInstrumentsNetPretax
Increase (decrease) from:      
Accounts receivable (7,092)us-gaap_IncreaseDecreaseInAccountsReceivable (1,305)us-gaap_IncreaseDecreaseInAccountsReceivable  
Inventory (560)us-gaap_IncreaseDecreaseInInventories (413)us-gaap_IncreaseDecreaseInInventories  
Other current assets (17,536)us-gaap_IncreaseDecreaseInOtherCurrentAssets (2,113)us-gaap_IncreaseDecreaseInOtherCurrentAssets (4,714)us-gaap_IncreaseDecreaseInOtherCurrentAssets
Other assets 2,645us-gaap_IncreaseDecreaseInOtherOperatingAssets (2,714)us-gaap_IncreaseDecreaseInOtherOperatingAssets  
Accounts payable (137)us-gaap_IncreaseDecreaseInAccountsPayable 2,478us-gaap_IncreaseDecreaseInAccountsPayable 2,664us-gaap_IncreaseDecreaseInAccountsPayable
Accrued compensation and benefits 8,317us-gaap_IncreaseDecreaseInEmployeeRelatedLiabilities 913us-gaap_IncreaseDecreaseInEmployeeRelatedLiabilities 10,656us-gaap_IncreaseDecreaseInEmployeeRelatedLiabilities
Accrued product development expenses (2,782)us-gaap_IncreaseDecreaseInAccruedLiabilities 2,679us-gaap_IncreaseDecreaseInAccruedLiabilities 2,113us-gaap_IncreaseDecreaseInAccruedLiabilities
Other accrued expenses 2,570us-gaap_IncreaseDecreaseInOtherAccruedLiabilities 1,340us-gaap_IncreaseDecreaseInOtherAccruedLiabilities 4,669us-gaap_IncreaseDecreaseInOtherAccruedLiabilities
Other liabilities 2,644us-gaap_IncreaseDecreaseInOtherOperatingLiabilities 14,834us-gaap_IncreaseDecreaseInOtherOperatingLiabilities 5,714us-gaap_IncreaseDecreaseInOtherOperatingLiabilities
Deferred revenue 82,801us-gaap_IncreaseDecreaseInDeferredRevenue 10us-gaap_IncreaseDecreaseInDeferredRevenue (230)us-gaap_IncreaseDecreaseInDeferredRevenue
Deferred executive compensation paid (2,630)aria_DeferredExecutiveCompensationPaid (3,953)aria_DeferredExecutiveCompensationPaid (1,063)aria_DeferredExecutiveCompensationPaid
Net cash used in operating activities (57,794)us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations (221,882)us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations (153,681)us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations
Cash flows from investing activities:      
Acquisitions of marketable securities     (89,554)us-gaap_PaymentsToAcquireAvailableForSaleSecurities
Proceeds from maturities of marketable securities   45,000us-gaap_ProceedsFromSaleAndMaturityOfMarketableSecurities 44,500us-gaap_ProceedsFromSaleAndMaturityOfMarketableSecurities
Change in restricted cash   (10,319)us-gaap_IncreaseDecreaseInRestrictedCash (289)us-gaap_IncreaseDecreaseInRestrictedCash
Investment in property and equipment (2,787)us-gaap_PaymentsToAcquireProductiveAssets (8,543)us-gaap_PaymentsToAcquireProductiveAssets (4,424)us-gaap_PaymentsToAcquireProductiveAssets
Gain on disposition of stock 4,768us-gaap_PaymentsForProceedsFromOtherInvestingActivities    
Investment in intangible assets     (633)us-gaap_PaymentsToAcquireIntangibleAssets
Net cash provided by (used in) investing activities 1,981us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperations 26,138us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperations (50,400)us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperations
Cash flows from financing activities:      
Proceeds from issuance of convertible debt, including equity component, net of issuance costs, $7,079,000 192,921us-gaap_ProceedsFromConvertibleDebt    
Proceeds from issuance of warrants 27,580us-gaap_ProceedsFromIssuanceOfWarrants    
Purchase of convertible bond hedges (43,220)us-gaap_PaymentsForHedgeFinancingActivities    
Repayment of long-term borrowings (9,100)us-gaap_RepaymentsOfLongTermDebt (2,100)us-gaap_RepaymentsOfLongTermDebt (1,400)us-gaap_RepaymentsOfLongTermDebt
Principal payments under capital lease obligations   (15)us-gaap_RepaymentsOfLongTermCapitalLeaseObligations (54)us-gaap_RepaymentsOfLongTermCapitalLeaseObligations
Proceeds from issuance of common stock, net of issuance costs   310,037us-gaap_ProceedsFromIssuanceOfCommonStock  
Reimbursements of amounts related to facility lease obligation   2,741aria_ProceedsFromLeaseFinancingObligation  
Proceeds from issuance of common stock pursuant to warrants     12,483us-gaap_ProceedsFromWarrantExercises
Proceeds from issuance of common stock pursuant to stock option and purchase plans 3,695us-gaap_ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions 6,284us-gaap_ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions 10,511us-gaap_ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions
Payment of tax withholding obligations related to stock compensation (816)us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation (3,363)us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation (4,336)us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation
Net cash provided by financing activities 171,060us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperations 313,584us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperations 17,204us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperations
Effect of exchange rates on cash 262us-gaap_EffectOfExchangeRateOnCashAndCashEquivalents (40)us-gaap_EffectOfExchangeRateOnCashAndCashEquivalents  
Net increase (decrease) in cash and cash equivalents 115,509us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease 117,800us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease (186,877)us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease
Cash and cash equivalents, beginning of year 237,179us-gaap_CashAndCashEquivalentsAtCarryingValue 119,379us-gaap_CashAndCashEquivalentsAtCarryingValue 306,256us-gaap_CashAndCashEquivalentsAtCarryingValue
Cash and cash equivalents, end of year 352,688us-gaap_CashAndCashEquivalentsAtCarryingValue 237,179us-gaap_CashAndCashEquivalentsAtCarryingValue 119,379us-gaap_CashAndCashEquivalentsAtCarryingValue
Supplemental disclosures:      
Interest paid 8,077us-gaap_InterestPaid 153us-gaap_InterestPaid 206us-gaap_InterestPaid
Income taxes paid 185us-gaap_IncomeTaxesPaid 17us-gaap_IncomeTaxesPaid  
Capitalization of construction-in-progress related to facility lease obligation 96,558aria_ConstructionInProgressNonCashExpendituresOnFacilityLease 96,671aria_ConstructionInProgressNonCashExpendituresOnFacilityLease  
Non-cash transaction - property and equipment included in accounts payable or accruals $ 298us-gaap_CapitalExpendituresIncurredButNotYetPaid $ 738us-gaap_CapitalExpendituresIncurredButNotYetPaid $ 579us-gaap_CapitalExpendituresIncurredButNotYetPaid