Income Taxes (Tables)

12 Months Ended

Dec. 31, 2014

Loss before Income Tax Provision and Income Tax Expense

Loss before provision for income taxes and the provision for income taxes consist of the following for the years ended December 31, 2014, 2013 and 2012:

In thousands	2014			2013			2012
Loss before provision for income taxes
Domestic	$	(100,860	)	$	(192,998	)	$	(182,974	)
Foreign		(61,112	)		(80,721	)		(37,898	)
Total	$	(161,972	)	$	(273,719	)	$	(220,872	)
Provision for income taxes
Current:
Federal	$	—		$	—		$	—
State		237			216			—
Foreign		393			223			—
Total	$	630		$	439		$	—

Reconciliation of Federal Statutory Corporate Income Tax Rate to Effective Income Tax Rate

A reconciliation of the federal statutory corporate income tax rate to the effective income tax rate for the years ended December 31, 2014, 2013 and 2012 is as follows:

	2014			2013			2012
Statutory federal income tax rate		(35	)%		(35	)%		(35	)%
State income tax rate, net of federal benefit		(4	)		(2	)		(4	)
Revaluation of warrant liability		—			—			3
Other permanent differences		(5	)		—			(1	)
Foreign rate differential		9			9			6
Change in valuation allowance		35			28			31
Effective tax rate		—	%		—	%		—	%

Components of Deferred Income Taxes

The components of deferred income taxes were as follows at December 31:

In thousands	2014			2013
Deferred tax liabilities:
Intangibles	$	377		$	388
Unrealized currency gain		—			10,892
Total deferred tax liabilities		377			11,280
Deferred tax assets:
Net operating loss carryforwards		205,793			166,951
Federal and state tax credit carryovers		32,318			28,645
Depreciation		4,383			3,607
Stock-based compensation		12,803			7,780
Other		9,008			7,977
Debt-related deductions		934			—
Total deferred tax assets		265,239			214,960
Deferred tax assets, net		264,862			203,680
Valuation allowance		(264,862	)		(203,680	)
Total deferred taxes	$	—		$	—

Estimated Net Operating Loss and Research and Development Credit Carryforwards

At December 31, 2014, the Company had available estimated net operating loss carryforwards and research and development credit carryforwards for federal, foreign and state tax reporting purposes as follows:

	Amount		Expiring if not utilized
	(in thousands)
Net operating loss carryforwards:
Federal	$	562,120		2024 through 2035
State	$	226,804		2034 through 2035
Foreign	$	194,944		2020 through 2022
Research and development credit carryforwards:
Federal	$	28,930		2019 through 2035
State	$	4,251		2026 through 2030

Reconciliation of Reserve for Uncertain Tax Benefits

A reconciliation of the reserve for uncertain tax benefits (including state tax matters without federal benefits) is as follows:

In thousands	2014		2013
Uncertain tax positions, beginning of the year:	$	24,653	$	24,404
Gross increases – tax positions in current period		331		249
Uncertain tax positions, end of year	$	24,984	$	24,653