Stock-Based Compensation (Tables)

6 Months Ended

Jun. 30, 2014

Total Compensation Cost from Share-Based Payments

The Company’s statements of operations included total compensation cost from share-based payments for the three-month and six-month periods ended June 30, 2014 and 2013, as follows:

In thousands	Three Months Ended June 30,				Six Months Ended June 30,
	2014		2013		2014		2013
Compensation cost from:
Stock options	$	4,164	$	4,751	$	8,844	$	8,112
Stock and stock units		4,178		9,445		7,826		11,592
Purchases of common stock at a discount		107		121		275		224
	$	8,449	$	14,317	$	16,945	$	19,928
Compensation cost included in:
Research and development expenses	$	3,633	$	5,762	$	7,341	$	8,416
Selling, general and administrative expenses		4,816		8,555		9,604		11,512
	$	8,449	$	14,317	$	16,945	$	19,928

Stock Option Activity

Stock option activity under the Company’s stock plans for the six-month period ended June 30, 2014 was as follows:

	Number of Shares			Weighted Average Exercise Price Per Share
Options outstanding, January 1, 2014		10,379,668		$	10.83
Granted		1,493,560		$	7.35
Forfeited		(1,036,902	)	$	14.25
Exercised		(368,446	)	$	4.20
Options outstanding, June 30, 2014		10,467,880		$	10.23

Stock and stock units

Stock and Stock Unit Activity

Stock and stock unit activity under the Company’s stock plans for the six-month period ended June, 2014 was as follows:

	Number of Shares			Weighted Average Grant Date Fair Value
Outstanding, January 1, 2014		2,047,600		$	14.18
Granted		2,479,500		$	7.35
Forfeited		(220,512	)	$	9.64
Vested or restrictions lapsed		(546,988	)	$	12.97
Outstanding, June 30, 2014		3,759,600		$	10.11