Nature of Business and Summary of Significant Accounting Policies - Additional Information (Detail) (USD $)	3 Months Ended	12 Months Ended			0 Months Ended	12 Months Ended
	Dec. 31, 2013	Dec. 31, 2013	Dec. 31, 2012 Customer	Dec. 31, 2011 Customer	Jan. 14, 2014 Subsequent Event	Dec. 31, 2013 Net product sales Customer	Dec. 31, 2013 Net product sales Customer One Product Sales	Dec. 31, 2013 Net product sales Customer Two Product Sales	Dec. 31, 2013 Net product sales Customer Three Product Sales	Dec. 31, 2013 Net product sales Outside the United States	Dec. 31, 2013 Accounts receivable Customer	Dec. 31, 2013 Accounts receivable Customer One Product Sales	Dec. 31, 2013 Accounts receivable Customer Two Product Sales	Dec. 31, 2013 Minimum	Dec. 31, 2013 Maximum
Schedule Of Significant Accounting Policies [Line Items]
Realized and unrealized foreign currency transaction losses recognized in earnings		$ 194,000
Property and equipment, useful life														3 years	10 years
Capitalized costs, amortization period maximum															17 years
Accrued rent	5,100,000	5,100,000	5,000,000
Accrued rent included in other long term liabilities	4,600,000	4,600,000	4,700,000
Accrued rent included in other current liabilities	500,000	500,000	300,000
Amount owed to former customer due to product returns		4,200,000
Customer prepayments	8,800,000	8,800,000
Value of shipment not recognized as revenue	4,100,000
Payment received on shipment	1,800,000	1,800,000
Number of customers accounted for net product sales						3
Number Of customers accounted for accounts receivable											2
Customers concentration risk, percentage							24.00%	15.00%	13.00%	9.00%		15.00%	13.00%
Number of customers related to revenue			1	1
Advertising costs		1,000,000
Tax benefit, minimum percentage of likelihood of being realized upon ultimate settlement		50.00%
Milestone payments for clinical trials					$ 3,800,000