CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (USD $) In Thousands, except Per Share data, unless otherwise specified	3 Months Ended		6 Months Ended
	Jun. 30, 2013	Jun. 30, 2012	Jun. 30, 2013	Jun. 30, 2012
Revenue:
Product revenue, net	$ 13,934		$ 20,298
License revenue	69	318	162	382
Service revenue	8		16	17
Total revenue	14,011	318	20,476	399
Operating expenses:
Cost of product revenue	228		497
Research and development expense	40,668	39,425	81,931	68,198
Selling, general and administrative expense	42,101	12,224	71,583	23,512
Total operating expenses	82,997	51,649	154,011	91,710
Loss from operations	(68,986)	(51,331)	(133,535)	(91,311)
Other income (expense):
Interest income	31	69	80	137
Interest expense	(39)	(50)	(80)	(108)
Revaluation of warrant liability				(15,924)
Foreign exchange gain	95		25
Other income (expense), net	87	19	25	(15,895)
Loss before provision for income taxes	(68,899)	(51,312)	(133,510)	(107,206)
Provision for income taxes	86		145
Net loss	$ (68,985)	$ (51,312)	$ (133,655)	$ (107,206)
Net loss per share - basic and diluted	$ (0.37)	$ (0.31)	$ (0.74)	$ (0.66)
Weighted-average number of shares of common stock outstanding - basic and diluted	184,726	165,848	181,651	163,409