Stock-Based Compensation (Tables)

6 Months Ended

Jun. 30, 2013

Total Compensation Cost from Share-Based Payments

The Company awards stock options and other equity-based instruments to its employees, directors and consultants and provides employees the right to purchase common stock (collectively “share-based payments”), pursuant to stockholder approved plans. The Company’s statements of operations included total compensation cost from share-based payments for the three-month and six-month periods ended June 30, 2013 and 2012, as follows:

	Three Months Ended				Six Months Ended
	June 30,				June 30,
In thousands	2013		2012		2013		2012
Compensation cost from:
Stock options	$	4,751	$	1,803	$	8,112	$	4,692
Stock and stock units		9,445		1,671		11,592		3,646
Purchases of common stock at a discount		121		57		224		106
	$	14,317	$	3,531	$	19,928	$	8,444
Compensation cost included in:
Research and development expenses	$	5,762	$	1,675	$	8,416	$	4,191
Selling, general and administrative expenses		8,555		1,856		11,512		4,253
	$	14,317	$	3,531	$	19,928	$	8,444

Stock Option Activity

Stock option activity under the Company’s stock plans for the six-month period ended June 30, 2013 was as follows:

	Number of Shares			Weighted Average Exercise  Price Per Share
Options outstanding, January 1, 2013		8,228,334		$	10.20
Granted		2,812,015		$	18.68
Forfeited		(69,839	)	$	16.86
Exercised		(330,790	)	$	5.10
Options outstanding, June 30, 2013		10,639,720		$	12.55

Stock and Stock Units

Stock and Stock Unit Activity

Stock and stock unit activity under the Company’s stock plans for the six-month period ended June, 2013 was as follows:

	Number of Shares			Weighted Average Grant  Date Fair Value
Outstanding, January 1, 2013		1,903,445		$	9.55
Granted		1,104,535		$	19.87
Forfeited		(9,234	)	$	9.79
Vested or restrictions lapsed		(926,157	)	$	7.41
Outstanding, June 30, 2013		2,072,589		$	16.00