Condensed Consolidated Balance Sheets (USD $) In Thousands, unless otherwise specified	Sep. 30, 2012	Dec. 31, 2011
Current assets:
Cash and cash equivalents	$ 141,619	$ 306,256
Marketable securities	65,041
Other current assets	4,769	1,311
Total current assets	211,429	307,567
Restricted cash	1,037	749
Property and equipment, net	7,583	6,611
Intangible and other assets, net	2,948	5,785
Total assets	222,997	320,712
Current liabilities:
Accounts payable	8,274	5,728
Current portion of long-term debt and capital lease obligations	1,952	1,454
Accrued compensation and benefits	6,066	1,209
Accrued product development expenses	13,338	11,948
Other accrued expenses	6,490	3,634
Current portion of deferred revenue	231	231
Current portion of deferred executive compensation	3,074	1,032
Other current liabilities	433	136
Total current liabilities	39,858	25,372
Long-term debt and capital lease obligations	9,625	11,215
Deferred revenue	595	768
Deferred executive compensation	1,881	2,723
Other long-term liabilities	6,375	1,854
Warrant liability		58,639
Stockholders' equity:
Preferred stock, $.01 par value; authorized 10,000,000 shares; none issued and outstanding
Common stock, $.001 par value; authorized 240,000,000 shares in 2012 and 2011; issued and outstanding 166,575,670 shares in 2012 and 157,608,702 shares in 2011	167	158
Additional paid-in capital	881,858	776,946
Accumulated other comprehensive loss	20
Accumulated deficit	(717,382)	(556,963)
Total stockholders' equity	164,663	220,141
Total liabilities and stockholders' equity	$ 222,997	$ 320,712