Stock-Based Compensation (Tables)

6 Months Ended

Jun. 30, 2012

Total Compensation Cost from Share-Based Payments

The Company’s statements of operations included total compensation cost from share-based payments for the three and six-month periods ended June 30, 2012 and 2011, as follows:

	Three Months Ended June  30,				Six Months Ended June 30,
In thousands	2012		2011		2012		2011
Compensation cost from:
Stock options	$	1,803	$	718	$	4,692	$	1,606
Stock and stock units		1,671		1,156		3,646		2,618
Purchases of common stock at a discount		57		43		106		97
	$	3,531	$	1,917	$	8,444	$	4,321
Compensation cost included in:
Research and development expenses	$	1,675	$	947	$	4,191	$	2,105
General and administrative expenses		1,856		970		4,253		2,216
	$	3,531	$	1,917	$	8,444	$	4,321

Stock Option Activity

Stock option activity under the Company’s stock plans for the six months ended June 30, 2012 was as follows:

	Number of Shares			Weighted Average Exercise  Price Per Share
Options outstanding, January 1, 2012		7,381,329		$	5.22
Granted		1,941,750		$	15.36
Forfeited		(18,563	)	$	6.34
Exercised		(1,248,837	)	$	4.39
Options outstanding, June 30, 2012		8,055,679		$	7.79

Stock and stock units

Stock and Stock Unit Activity

Stock and stock unit activity under the Company’s stock plans for the six months ended June 30, 2012 was as follows:

	Number of Shares			Weighted Average Grant  Date Fair Value
Outstanding, January 1, 2012		2,785,026		$	4.51
Granted		911,677		$	15.02
Forfeited		(6,800	)	$	4.13
Vested or restrictions lapsed		(1,551,242	)	$	4.08
Outstanding, June 30, 2012		2,138,661		$	9.31