Stock-Based Compensation (Tables)

3 Months Ended

Mar. 31, 2012

Total Compensation Cost from Share-Based Payments

The Company’s statement of operations included total compensation cost from share-based payments for the three-month periods ended March 31, 2012 and 2011, as follows:

	Three Months Ended March  31,
In thousands	2012		2011
Compensation cost from:
Stock options	$	2,889	$	889
Stock and stock units		1,975		1,461
Purchases of common stock at a discount		49		54
	$	4,913	$	2,404
Compensation cost included in:
Research and development expenses	$	2,516	$	1,158
General and administrative expenses		2,397		1,246
	$	4,913	$	2,404

Stock Option Activity

Stock option activity under the Company’s stock plans for the year ended March 31, 2012 was as follows:

	Number of Shares			Weighted Average Exercise  Price Per Share
Options outstanding, January 1, 2012		7,381,329		$	5.22
Granted		1,531,750		$	14.90
Forfeited		(12,063	)	$	2.89
Exercised		(775,107	)	$	4.23
Options outstanding, March 31, 2012		8,125,909		$	7.14

Stock and stock units

Stock and Stock Unit Activity

Stock and stock unit activity under the Company’s stock plans for the year ended March 31, 2012 was as follows:

	Number of Shares			Weighted Average Grant  Date Fair Value
Outstanding, January 1, 2012		2,785,026		$	4.51
Granted		901,677		$	15.00
Forfeited		(6,800	)	$	4.13
Vested or restrictions lapsed		(1,420,406	)	$	3.73
Outstanding, March 31, 2012		2,259,497		$	9.19