CONSOLIDATED BALANCE SHEETS (USD $) In Thousands, unless otherwise specified	Dec. 31, 2011	Dec. 31, 2010
Current assets:
Cash and cash equivalents	$ 306,256	$ 103,630
Amounts due under license agreements (Note 2)	34	407
Other current assets	1,277	1,135
Total current assets	307,567	105,172
Restricted cash	749	749
Property and equipment, net (Note 3)	6,611	7,037
Intangible and other assets, net (Note 4)	5,785	7,072
Total assets	320,712	120,030
Current liabilities:
Accounts payable	5,728	3,122
Current portion of long-term debt and capital lease obligations (Note 5)	1,454	1,466
Accrued compensation and benefits	1,209	1,127
Accrued product development expenses	11,948	8,189
Other accrued expenses	3,634	1,664
Current portion of deferred executive compensation (Note 6)	1,032	693
Current portion of deferred revenue	231
Other current liabilities	136	136
Total current liabilities	25,372	16,397
Long-term debt and capital lease obligations (Note 5)	11,215	8,294
Other long-term liabilities	1,854	330
Deferred revenue	768
Deferred executive compensation (Note 6)	2,723	2,118
Warrant liability (Notes 8 and 9)	58,639	28,815
Commitments (Note 7)
Stockholders' equity (Notes 8, 10 and 11):
Preferred stock, $.01 par value, authorized 10,000,000 shares, none issued and outstanding
Common stock, $.001 par value, authorized 240,000,000 shares in 2011 and 2010; shares issued and outstanding 157,608,702 shares in 2011, 126,942,431 shares in 2010	158	127
Additional paid-in capital	776,946	497,309
Accumulated deficit	(556,963)	(433,360)
Total stockholders' equity	220,141	64,076
Total liabilities and stockholders' equity	$ 320,712	$ 120,030