CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (USD $) In Thousands, except Per Share data	3 Months Ended		9 Months Ended
	Sep. 30, 2011	Sep. 30, 2010	Sep. 30, 2011	Sep. 30, 2010
Revenue:
License and collaboration revenue	$ 25,084	$ 37	$ 25,122	$ 174,447
Service revenue	17	1,205	100	3,997
Total revenue	25,101	1,242	25,222	178,444
Operating expenses:
Research and development	19,692	13,168	53,020	41,817
General and administrative	6,329	3,670	17,334	12,245
Total operating expenses	26,021	16,838	70,354	54,062
Income (loss) from operations	(920)	(15,596)	(45,132)	124,382
Other income (expense):
Interest income	33	29	132	51
Interest expense	(49)	(52)	(172)	(160)
Revaluation of warrant liability	14,846	(4,781)	(26,629)	(8,723)
Other income (expense), net	14,830	(4,804)	(26,669)	(8,832)
Net income (loss)	$ 13,910	$ (20,400)	$ (71,801)	$ 115,550
Net income (loss) per share - basic	$ 0.10	$ (0.18)	$ (0.55)	$ 1.05
- diluted	$ 0.10	$ (0.18)	$ (0.55)	$ 1.04
Weighted-average number of shares of common stock outstanding - basic	132,587	110,810	131,215	110,045
- diluted	137,480	110,810	131,215	111,556