-----BEGIN PRIVACY-ENHANCED MESSAGE----- Proc-Type: 2001,MIC-CLEAR Originator-Name: webmaster@www.sec.gov Originator-Key-Asymmetric: MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB MIC-Info: RSA-MD5,RSA, N0Ii2jqfXTedJyXZ2NCeDOWJnDkBXZTsKM8fzI1xyVsdfkfmcWVbt/hBvSPiqpl5 zKjZBzfUTLl47naynEqLFQ== 0000950135-98-004497.txt : 19980807 0000950135-98-004497.hdr.sgml : 19980807 ACCESSION NUMBER: 0000950135-98-004497 CONFORMED SUBMISSION TYPE: 10-Q PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 19980630 FILED AS OF DATE: 19980806 SROS: NASD FILER: COMPANY DATA: COMPANY CONFORMED NAME: ARIAD PHARMACEUTICALS INC CENTRAL INDEX KEY: 0000884731 STANDARD INDUSTRIAL CLASSIFICATION: BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836] IRS NUMBER: 223106987 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 10-Q SEC ACT: SEC FILE NUMBER: 000-21696 FILM NUMBER: 98677990 BUSINESS ADDRESS: STREET 1: 26 LANDSDOWNE ST CITY: CAMBRIDGE STATE: MA ZIP: 02139 BUSINESS PHONE: 6174940400 MAIL ADDRESS: STREET 2: 26 LANDSDOWNE CITY: CAMBRIDGE STATE: MA ZIP: 02139 10-Q 1 ARIAD PHARMACEUTICALS, INC. 1 ================================================================================ SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q [X] QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE QUARTERLY PERIOD ENDED: JUNE 30, 1998 OR [ ] TRANSITION REPORT PURSUANT TO SECTION 13 OR 15 (d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM _____ TO _____ COMMISSION FILE NUMBER: 0-21696 ARIAD PHARMACEUTICALS, INC. (Exact name of Registrant as specified in its charter) DELAWARE 22-3106987 (State or other jurisdiction of (I.R.S. Employer incorporation or organization) Identification No.) 26 LANDSDOWNE STREET, CAMBRIDGE, MASSACHUSETTS 02139 (Address of principal executive offices)(Zip Code) REGISTRANT'S TELEPHONE NUMBER, INCLUDING AREA CODE: (617) 494-0400 Former Name, Former Address and Former Fiscal Year, If Changed Since Last Report: Not Applicable Indicate by check mark whether the Registrant (1) has filed all reports required to be filed by Section 13 or 15 (d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the Registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days. YES [X] NO [ ] The number of shares of the Registrant's common stock outstanding as of August 1, 1998 was 21,882,270. ================================================================================ 2 ARIAD PHARMACEUTICALS, INC. TABLE OF CONTENTS PART I. FINANCIAL INFORMATION Page No. - ------------------------------ ------- ITEM 1. UNAUDITED FINANCIAL STATEMENTS: Condensed Consolidated Balance Sheets - June 30, 1998 and December 31, 1997 ............................................. 1 Condensed Consolidated Statements of Operations for the Three Months and Six Months Ended June 30, 1998 and 1997 .......... 2 Condensed Consolidated Statements of Cash Flows for the Six Months Ended June 30, 1998 and 1997 ........................... 3 Notes to Unaudited Condensed Consolidated Financial Statements .............................................. 4 ITEM 2. MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS ............................... 6 PART II. OTHER INFORMATION - -------------------------- ITEM 4. SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS ............... 11 ITEM 5. OTHER INFORMATION ................................................. 11 ITEM 6. EXHIBITS AND REPORTS ON FORM 8-K .................................. 11 3 PART I. FINANCIAL INFORMATION ITEM 1. UNAUDITED FINANCIAL STATEMENTS ARIAD PHARMACEUTICALS, INC. AND SUBSIDIARIES CONDENSED CONSOLIDATED BALANCE SHEETS (UNAUDITED)
ASSETS JUNE 30, DECEMBER 31, 1998 1997 ------------ ------------ Current assets: Cash and cash equivalents $ 8,499,005 $ 13,858,910 Marketable securities 13,926,520 15,500,547 Prepaid expenses, inventory and other assets 2,653,880 758,463 ------------ ------------ Total current assets 25,079,405 30,117,920 ------------ ------------ Property and equipment: Leasehold improvements 12,537,800 12,350,100 Equipment and furniture 4,620,519 5,549,127 ------------ ------------ Total 17,158,319 17,899,227 Less accumulated depreciation and amortization 7,702,414 6,459,857 ------------ ------------ Property and equipment, net 9,455,905 11,439,370 ------------ ------------ Investment in Genomics Center 2,444,913 1,418,864 ------------ ------------ Intangible and other assets, net 4,339,483 4,433,022 ------------ ------------ Total $ 41,319,706 $ 47,409,176 ============ ============ LIABILITIES AND STOCKHOLDERS' EQUITY Current liabilities: Current portion of long-term debt $ 1,838,304 $ 1,816,583 Accounts payable 3,086,912 3,299,168 Accrued liabilities 1,719,382 2,849,353 Advance from Genomics Center 2,918,312 2,502,921 Deferred revenue 1,444,448 3,111,114 ------------ ------------ Total current liabilities 11,007,358 13,579,139 ------------ ------------ Long-term debt 4,231,486 5,156,219 ------------ ------------ Deferred revenue 300,000 ------------ Stockholders' equity: Series B convertible preferred stock, $.01 par value; authorized, 5,000,000 shares; issued and outstanding, 2,526,316 shares in 1998 and 1997 (liquidation preference, $24,000,000) 25,263 25,263 Common stock, $.001 par value; authorized, 60,000,000 shares; issued and outstanding, 21,882,270 shares in 1998 and 19,308,605 shares in 1997 21,882 19,309 Additional paid-in capital 104,207,475 94,833,479 Net unrealized loss on marketable securities (40,497) (47,572) Accumulated deficit (78,133,261) (66,456,661) ------------ ------------ Stockholders' equity 26,080,862 28,373,818 ------------ ------------ Total $ 41,319,706 $ 47,409,176 ============ ============
See notes to unaudited condensed consolidated financial statements. 1 4 ARIAD PHARMACEUTICALS, INC. AND SUBSIDIARIES CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (UNAUDITED)
THREE MONTHS ENDED SIX MONTHS ENDED JUNE 30, JUNE 30, ------------------------- --------------------------- 1998 1997 1998 1997 ----------- ----------- ------------ ----------- Revenue: Research revenue (principally related parties) $ 3,227,883 $ 2,489,209 $ 6,074,469 $ 4,462,542 Interest income 295,702 525,213 608,747 817,930 ----------- ----------- ------------ ----------- Total revenue 3,523,585 3,014,422 6,683,216 5,280,472 ----------- ----------- ------------ ----------- Operating expenses: Research and development 8,989,688 4,273,087 16,725,643 8,530,228 General and administrative 677,020 725,817 1,376,049 1,483,882 Interest expense 127,542 54,038 258,124 111,513 ----------- ----------- ------------ ----------- Total operating expenses 9,794,250 5,052,942 18,359,816 10,125,623 ----------- ----------- ------------ ----------- Net loss $(6,270,665) $(2,038,520) $(11,676,600) $(4,845,151) =========== =========== ============ =========== Net loss per share (basic and diluted) $ (.30) $ (.11) $ (.58) $ (.25) =========== =========== ============ =========== Weighted average number of shares of common stock outstanding 20,732,321 19,264,673 20,025,138 19,205,125
See notes to unaudited condensed consolidated financial statements. 2 5 ARIAD PHARMACEUTICALS, INC. AND SUBSIDIARIES CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (UNAUDITED)
SIX MONTHS ENDED JUNE 30, ----------------------------- 1998 1997 ------------ ------------ Cash flows from operating activities: Net loss $(11,676,600) $ (4,845,151) Adjustments to reconcile net loss to net cash used in operating activities: Depreciation and amortization 1,696,616 1,181,444 Deferred revenue (1,966,666) (1,666,666) Stock-based compensation 35,151 35,151 Increase (decrease) from: Prepaid expenses, inventory and other current assets (1,895,417) (69,399) Accounts receivable-related party 2,000,000 Other assets 81,328 (84,630) Accounts payable (212,256) 1,679,845 Accrued liabilities (1,129,971) 151,200 Advance from Genomics Center 415,391 1,205,272 ------------ ------------ Net cash used in operating activities (14,652,424) (412,934) ------------ ------------ Cash flows from investing activities: Acquisitions of marketable securities (10,373,591) (18,126,062) Proceeds from sales and maturities of marketable securities 11,903,013 10,589,470 Investment in Genomics Center (3,043,992) (806,891) Return of investment in Genomics Center 1,998,303 Investment in property and equipment, net (1,406,502) (3,574,819) Acquisitions of licensed technology and patents (370,524) (258,272) ------------ ------------ Net cash used in investing activities (1,293,293) (12,176,574) ------------ ------------ Cash flows from financing activities: Proceeds from issuance of common stock, net of issuance costs 9,243,622 Proceeds from issuance of series B preferred stock 24,000,000 Repayment of borrowings (903,012) (983,122) Proceeds from borrowings 6,000,000 Proceeds from sale/leaseback of equipment 2,147,410 Proceeds from exercise of stock options 97,792 123,224 ------------ ------------ Net cash provided by financing activities 10,585,812 29,140,102 ------------ ------------ Net (decrease) increase in cash and equivalents (5,359,905) 16,550,594 Cash and equivalents, beginning of period 13,858,910 2,906,851 ------------ ------------ Cash and equivalents, end of period $ 8,499,005 $ 19,457,445 ============ ============
See notes to unaudited condensed consolidated financial statements. 3 6 ARIAD PHARMACEUTICALS, INC. AND SUBSIDIARIES NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS 1. MANAGEMENT STATEMENT In the opinion of the Company's management, the accompanying unaudited condensed consolidated financial statements contain all adjustments (consisting of only normal recurring accruals) necessary to present fairly the financial position as of June 30, 1998 and December 31, 1997 and the results of operations for the three-month and six-month periods ended June 30, 1998 and 1997. The results of operations for the three-month and six-month periods ended June 30, 1998 are not necessarily indicative of the results to be expected for the full year. 2. MARKETABLE SECURITIES The Company has classified its marketable securities as available for sale and, accordingly, carries such securities at aggregate fair value. At June 30, 1998 and December 31, 1997, the Company's marketable securities consisted of the following:
Aggregate Amortized Gross Unrealized 1998 Fair Value Cost Basis Gains Losses ---- ---------- ---------- ----- ------ U.S. Government obligations $ 783,346 $ 801,436 $(18,090) Corporate debt securities 13,143,174 13,165,581 $1,652 (24,059) ----------- ----------- ------ -------- Total $13,926,520 $13,967,017 $1,652 $(42,149) =========== =========== ====== ======== 1997 ---- U.S. Government obligations $ 2,974,292 $ 3,006,012 $(31,720) Corporate debt securities 12,526,255 12,542,107 $2,680 (18,532) ----------- ----------- ------ -------- Total $15,500,547 $15,548,119 $2,680 $(50,252) =========== =========== ====== ========
At June 30, 1998, approximately $11,320,000 of investments in marketable securities had contractual maturities of one year or less. Realized gains and losses on sales of marketable securities were not material during the quarter ended June 30, 1998; the net unrealized loss of $40,497 is included in stockholders' equity. 3. INVENTORY Inventories are carried at cost using the first-in, first-out method and are charged to research and development expense when consumed. Inventory consisted of bulk pharmaceutical material to be used for multiple preclinical and clinical drug development programs and amounted to $1,284,000 at June 30, 1998. 4 7 4. NET LOSS PER SHARE Net loss per share amounts have been computed based on the weighted average number of shares outstanding during each period. Because of the net loss reported in each period, diluted and basic per share amounts are the same. 5. HOECHST-ARIAD GENOMICS CENTER, LLC In March 1997, the Company entered into an agreement which established a 50/50 joint venture with Hoechst Marion Roussel ("HMR") to pursue functional genomics with the goal of identifying genes that encode novel therapeutic proteins and small-molecule drug targets (the "1997 HMR Genomics Agreement"). The joint venture, named the Hoechst-ARIAD Genomics Center, LLC (the "Genomics Center"), is located at the Company's research facilities in Cambridge, Massachusetts. Under the terms of the 1997 HMR Genomics Agreement, the Company and HMR agreed to commit $85,000,000 to the establishment of the Genomics Center and its first five years of operation. The Company and HMR agreed to jointly fund $78,500,000 of operating and related costs, and ARIAD agreed to invest up to $6,500,000 in leasehold improvements and equipment for use by ARIAD in conducting research on behalf of the Genomics Center. HMR committed to provide ARIAD with capital adequate to fund ARIAD's share of such costs through the purchase of up to $49,000,000 of ARIAD series B preferred stock over the five-year period, including an initial investment of $24,000,000, which was completed in March 1997. From the formation of the Genomics Center through June 30, 1998, the Company invested $6,500,000 in leasehold improvements and equipment and funded $5,646,000 in operating and related costs. Should ARIAD and HMR determine that the Genomics Center requires funds in excess of those committed, ARIAD may fund its share of the excess through a loan facility made available by HMR. Funds borrowed by ARIAD pursuant to such loan facility, if any, will bear interest at the ninety (90) day LIBOR rate plus 0.25% and are repayable by 2003 in cash or series B preferred stock, at the Company's option. The Company also entered into agreements with the Genomics Center to provide research and administrative services (the "Services Agreements") to the Genomics Center on a cost reimbursement basis. ARIAD's costs of providing the research and administrative services to the Genomics Center are charged to research and development expense and general and administrative expense in the consolidated financial statements. Under the Services Agreements, ARIAD bills the Genomics Center for 100% of its costs of providing the research and administrative services; however, because ARIAD is providing 50% of the funding of the Genomics Center, ARIAD recognizes as revenue only 50% of the billings to the Genomics Center. The remaining 50% is accounted for as a return of ARIAD's investment in the Genomics Center. Revenue recognized pursuant to the Services Agreements amounted to $1,998,000 and $378,000 for the six months ended June 30, 1998 and June 30, 1997, respectively. The Genomics Center had total assets of $4,481,000 at June 30, 1998 and incurred a net loss of $2,203,000 and $4,114,000 for the three-months and six-months ended June 30, 1998, respectively. 6. STOCKHOLDERS' EQUITY On May 11, 1998, the Company completed a private placement of 2,537,500 shares of common stock to a group of institutional investors at a price of $4.00 per share and received net proceeds of approximately $9.2 million after deducting selling commissions and offering expenses. The shares were registered under the Securities Act of 1933, as amended. 5 8 7. NEW ACCOUNTING PRONOUNCEMENTS Effective January 1, 1998, the Company adopted SFAS No. 130, Reporting Comprehensive Income, which requires businesses to disclose comprehensive income and its components in their general-purpose financial statements. In accordance with SFAS No. 130, the comprehensive loss for the second quarter of 1998 would include the net unrealized gain on marketable securities of $7,075 for the six months ended June 30, 1998, resulting in a comprehensive loss of $11,669,525. SFAS No. 131, Disclosures about Segments of an Enterprise and Related Information, which redefines how operating segments are determined and requires disclosure of certain financial and descriptive information about a company's operating segments, will be effective for the Company's financial statements for the year ending December 31, 1998. The Company has not yet completed its analysis of whether operating segment reporting will be required. ITEM 2. MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS OVERVIEW ARIAD Pharmaceuticals, Inc. (the "Company" or "ARIAD") is engaged in the discovery and development of novel, orally administered pharmaceuticals based on signal transduction technology. ARIAD's comprehensive and integrated drug-discovery platform spans from target identification and validation (functional genomics), to structure-based drug design and combinatorial chemistry, to medicinal chemistry and pharmacology. This "gene-to-drug" research and development capability forms the basis for multiple business opportunities, each with a diversity of potential products. ARIAD is currently focusing its drug discovery efforts on (i) the development of orally administered drugs to block signal transduction pathways that play a critical role in major diseases such as osteoporosis, immune-related diseases and allergy/asthma, and (ii) the development of orally active therapeutic proteins based on a system that controls signal transduction pathways in genetically engineered cells. These drug discovery efforts are based on validated small-molecule drug targets and known therapeutic proteins. ARIAD is further building its gene-to-drug research and development capability by expanding its functional genomics program. The Company employs functional genomics to identify new drug targets for its signal transduction inhibitor program and novel proteins for its orally active therapeutic protein program. In each area of drug discovery, as well as in functional genomics, the Company has entered into a significant strategic alliance with a collaborator to complement its gene and drug discovery technologies or to support its commercialization efforts. Since its inception in 1991, the Company has devoted substantially all of its resources to its research and development programs. The Company receives no revenue from the sale of pharmaceutical products and substantially all revenue to date has been received in connection with the Company's research collaborations. The Company has not been profitable since inception and expects to incur substantial and increasing operating losses for the foreseeable future, primarily due to the expansion of its research and development programs, including the services the Company provides to the Genomics Center pursuant to the Services Agreements, which services are accounted for on a cost reimbursement basis. The Company expects that losses will fluctuate from quarter to quarter and that such fluctuations may be substantial. As of June 30, 1998, the Company had an accumulated deficit of $78,133,000. 6 9 RESULTS OF OPERATIONS THREE MONTHS ENDED JUNE 30, 1998 COMPARED WITH THE THREE MONTHS ENDED JUNE 30, 1997 REVENUE The Company recognized research revenue of $3,228,000 for the quarter ended June 30, 1998 compared to $2,489,000 for the same period in 1997. Research revenue in 1998 is comprised principally of research revenue from services provided to the Genomics Center and the Company's 1995 collaborative research and development agreement with HMR (the "1995 HMR Osteoporosis Agreement"). The increase in research revenue of $739,000 for the quarter ended June 30, 1998 compared to the corresponding period in 1997 is a result of increased services provided to the Genomics Center, which services commenced in the second quarter of 1997. Research revenue resulting from the Services Agreements with the Genomics Center is expected to increase over the next two years, and research revenue recognized under the 1995 HMR Osteoporosis Agreement is expected to remain substantially equivalent in 1998. Interest income decreased by $229,000 to $296,000 for the quarter ended June 30, 1998 compared to $525,000 for the same period in 1997 primarily as a result of lower levels of funds invested during the period. OPERATING EXPENSES Research and development expenses increased to $8,990,000 for the quarter ended June 30, 1998 compared to $4,273,000 for the same period in 1997 due primarily to research services provided to the Genomics Center under the Services Agreements and increased expenses in the orally active protein therapy program, including manufacturing development and other preclinical development costs. The Company expects its research and development expenses to increase substantially over the next two years as a result of research services to be provided to the Genomics Center as well as increased manufacturing and preclinical development costs associated with its drug candidates and, if such preclinical studies are successful, the subsequent cost of human clinical trials. General and administrative expenses decreased to $677,000 for the quarter ended June 30, 1998 compared to $726,000 for the corresponding period in 1997 primarily due to the nonrecurrence in 1998 of administrative expenses related to the formation of the Genomics Center in 1997. The Company incurred interest expense of $128,000 for the quarter ended June 30, 1998 compared to $54,000 for the corresponding period in 1997. The increase resulted from a higher level of long-term debt during the period. OPERATING RESULTS The Company incurred losses of $6,271,000 for the quarter ended June 30, 1998 and $2,039,000 for the corresponding period in 1997, or $.30 and $.11 per share, respectively. The Company expects that substantial operating losses will continue for several more years, will increase as its drug development activities expand and increased research services are provided to the Genomics Center and will fluctuate as a result of differences in the timing and composition of revenue earned and expenses incurred. 7 10 SIX MONTHS ENDED JUNE 30, 1998 COMPARED WITH THE SIX MONTHS ENDED JUNE 30, 1997 REVENUE Revenue for the six months ended June 30, 1998 were $6,683,000 compared to $5,280,000 for the corresponding period in 1997. Research revenue earned in 1998 increased by $1,612,000 over 1997 as a result of increased research and administrative services provided to the Genomics Center. Interest income for the six months ended June 30, 1998 decreased by $209,000 over the corresponding period in 1997 primarily as a result of a lower level of funds invested. OPERATING EXPENSES Research and development expenses increased to $16,726,000 for the six months ended June 30, 1998 from $8,530,000 for the corresponding period in 1997, primarily due to research services provided to the Genomics Center under the Services Agreements and increased expenses incurred in the orally active protein therapy program, including manufacturing development and other preclinical development costs. General and administrative expenses decreased to $1,376,000 for the six months ended June 30, 1998 compared to $1,484,000 for the corresponding period in 1997, primarily due to the nonrecurrence in 1998 of administrative expenses incurred in connection with the formation of the Genomics Center in 1997. The Company incurred interest expense of $258,000 for the six months ended June 30, 1998 compared to $112,000 for the corresponding period in 1997 as a result of a higher level of long-term debt. OPERATING RESULTS The Company incurred losses of $11,677,000 for the six months ended June 30, 1998 and $4,845,000 for the corresponding period in 1997, or $.58 and $.25 per share, respectively. The Company expects that substantial operating losses will continue for several more years, will increase as its drug development activities expand and increased research services are provided to the Genomics Center and will fluctuate as a result of differences in the timing and composition of revenue earned and expenses incurred. LIQUIDITY AND CAPITAL RESOURCES The Company has financed its operations and investments in property and equipment primarily through the private placement and public offering of its securities, including the sale of series B preferred stock to HMR, supplemented by the issuance of long-term debt, sale/leaseback and capital lease transactions, interest income, government-sponsored research grants and research revenue under the 1995 HMR Osteoporosis Agreement and the 1997 HMR Genomics Agreement. As of June 30, 1998, the Company had cash, cash equivalents and marketable securities totaling $22,426,000, and working capital of $14,072,000 compared to cash, cash equivalents and marketable securities totaling $29,359,000 and working capital amounting to $16,539,000 at December 31, 1997. The primary uses of cash during the six months ended June 30, 1998 were $14,652,000 to finance the Company's operations and working capital requirements, including an annual 8 11 payment of $3,000,000 for access to various genomics databases, $1,407,000 to purchase laboratory equipment, $903,000 to repay long-term debt, $1,046,000 for net investment in the Genomics Center and $371,000 to acquire intellectual property. The primary sources of cash during the six months ended June 30, 1998 were $9,244,000 in net proceeds from the private placement of common stock, $4,985,000 in advances from the Genomics Center, $2,000,000 of research funding from the 1995 HMR Osteoporosis Agreement, $2,147,000 from the sale/leaseback of laboratory equipment and $1,529,000 of net proceeds from the sale and maturity of marketable securities. On May 11 , 1998, the Company completed a private placement of 2,537,500 shares of common stock to a group of institutional investors at a price of $4.00 per share and received net proceeds of approximately $9.2 million after deducting selling commissions and offering expenses. The shares were registered under the Securities Act of 1933, as amended. In March 1997, the Company entered into a 50/50 joint venture with HMR to pursue functional genomics with the goal of identifying genes that encode novel therapeutic proteins and small-molecule drug targets. The Company and HMR agreed to commit up to $85,000,000 to the establishment of the Genomics Center and its first five years of operation. The Company and HMR agreed to jointly fund $78,500,000 of operating and related costs, and ARIAD agreed to fund up to $6,500,000 in leasehold improvements and equipment for use by ARIAD in conducting research on behalf of the Genomics Center. HMR committed to provide ARIAD with capital adequate to fund ARIAD's share of such costs through the purchase of up to $49,000,000 of series B preferred stock over the five-year period, including an initial investment of $24,000,000. From the formation of the Genomics Center through June 30, 1998, the Company invested $6,500,000 in leasehold improvements and equipment and funded $5,646,000 in operating and related costs. Pursuant to the 1997 HMR Genomics Agreement, on March 18, 1997, HMR purchased 2,526,316 shares of the Company's series B preferred stock for $24,000,000. During the period from 1999 to 2002, to fund its commitment to the Genomics Center, the Company may, at its option, require HMR to make additional purchases of up to $25,000,000 of series B preferred stock at purchase prices based on a premium to the market price of the common stock at the time of each subsequent purchase (unless the market price of the common stock exceeds a predetermined ceiling, in which case the purchase price will be equal to the market price). Should ARIAD and HMR determine that the Genomics Center requires funds in excess of those committed, ARIAD may fund its share of the excess through a loan facility made available by HMR. Funds borrowed by ARIAD pursuant to such loan facility, if any, will bear interest at the ninety (90) day LIBOR rate plus 0.25% and are repayable by 2003 in cash or series B preferred stock, at the Company's option. The Company will require substantial additional funding for its research and product development programs, for operating expenses, for the pursuit of regulatory clearances and for building manufacturing, sales and marketing capabilities. Adequate funds for these purposes, whether obtained through financial markets or collaborative or other arrangements with corporate partners, or from other sources, may not be available when needed or on terms acceptable to the Company. The Company believes that its available cash and existing sources of funding will be adequate to satisfy its capital and operating requirements for the next nine months. However, there can be no assurance that changes in the Company's research and development plans or other events affecting the Company's operating expenses will not result in the Company depleting its funds earlier. 9 12 SECURITIES LITIGATION REFORM ACT Safe harbor statement under the Private Securities Litigation Reform Act of 1995: Except for the historical information contained in this Quarterly Report on Form 10-Q, the matters discussed herein are forward-looking statements that involve risks and uncertainties, including but not limited to risks and uncertainties regarding the receipt of revenues under the Company's 1995 HMR Osteoporosis Agreement and the Services Agreements, the actual research and development expenses and other costs associated with the Genomics Center, the success of the Company's preclinical studies, the ability of the Company to commence clinical studies, the adequacy of the Company's capital resources and the availability of additional funding, as well as general economic, competitive, governmental and technological factors affecting the Company's operations, markets, products, services and prices, and other factors discussed under the heading "Cautionary Statement Regarding Forward-Looking Statements" in the Company's Annual Report on Form 10-K filed with the Securities and Exchange Commission. As a result of these factors, actual events or results could differ materially from those described herein. 10 13 PART II. OTHER INFORMATION ITEM 4. SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS The Annual Meeting of Stockholders was held on June 11, 1998. Of 21,878,868 shares issued and outstanding and eligible to vote as of the record date of April 14, 1998, a quorum of 18,852,504 shares or 86.17% of the eligible shares were present in person or represented by proxy. The only action taken at such meeting was the reelection of the following Class 1 Directors:
Number of Shares -------------------------------- For Withheld Authority ---------- ------------------ Joan S. Brugge, Ph.D. 18,751,957 100,547 John M. Deutch, Ph.D. 18,752,150 100,354
Continuing Class 2 Directors (terms to expire 1999): Philip Felig, M.D. Jay R. LaMarche Joel S. Marcus Continuing Class 3 Directors (terms to expire 2000): Harvey J. Berger, M.D. Vaughn D. Bryson Sandford D. Smith Raymond S. Troubh ITEM 5. OTHER INFORMATION Stockholders who wish to have their proposals presented at the 1999 Annual Meeting of Stockholders must deliver such proposals in writing to the Secretary of the Company at the Company's principal executive offices no later than December 1, 1998 for inclusion in the Company's proxy statement and form of proxy relating to that meeting. Stockholders who do not wish to include their proposals in such proxy statement and form of proxy but who wish to present proposals at the Company's 1999 Annual Meeting of Stockholders must notify the Secretary of the Company in writing at the Company's principal executive offices no later than March 2, 1999 in order for their proposals to be considered timely for purposes of Rule 14a-4 under the Securities Exchange Act of 1934, as amended. ITEM 6. EXHIBITS AND REPORTS ON FORM 8-K (a) Exhibits The following exhibit is filed herewith: 27.1 Financial Data Schedule (b) Reports on Form 8-K The Company filed a report on Form 8-K on April 29, 1998 to report the private placement of 2,537,500 shares of common stock. 11 14 SIGNATURES Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized. ARIAD Pharmaceuticals, Inc. (Registrant) By: /s/ Jay R. LaMarche ---------------------------------------- Jay R. LaMarche Executive Vice President and Chief Financial Officer (Duly authorized Officer and Principal Financial Officer) Date: August 6, 1998 12 15 EXHIBIT INDEX EXHIBIT NO. TITLE 3.1 CERTIFICATE OF INCORPORATION OF THE COMPANY, AS AMENDED(1) 3.2 BY-LAWS OF THE COMPANY, AS AMENDED(1) 3.3 AMENDMENT OF CERTIFICATE OF INCORPORATION OF THE COMPANY, DATED APRIL 8, 1994(2) 3.4 AMENDMENT OF CERTIFICATE OF INCORPORATION OF THE COMPANY, DATED OCTOBER 4, 1994(5) 3.5 CERTIFICATE OF DESIGNATIONS IN RESPECT OF SERIES B PREFERRED STOCK OF THE COMPANY(8) 3.6 AMENDMENT OF BY-LAWS OF THE COMPANY, ADOPTED SEPTEMBER 16, 1994(5) 4.1 FORM OF ARIAD PHARMACEUTICALS, INC. COMMON STOCK PURCHASE WARRANT(1) 4.2 PRINCIPAL STOCKHOLDERS' AGREEMENT, DATED AS OF JANUARY 5, 1992, AMONG ARIAD PHARMACEUTICALS, INC., DAVID BLECH, DAVID BLECH AS TRUSTEE OF THE BLECH FAMILY TRUST, MARK S. GERMAIN, HARVEY J. BERGER, HARVEY J. BERGER AND WENDY S. BERGER AS TRUSTEES OF THE BERGER FAMILY TRUST, AVALON VENTURES AND AVALON VENTURES IV.(1) 4.3 FORM OF WARRANT AGREEMENT (WITH FORM OF WARRANT).(3) 4.4 RIGHTS AGREEMENT, DATED AS OF DECEMBER 15, 1994, BETWEEN THE COMPANY AND STATE STREET BANK AND TRUST COMPANY, WHICH INCLUDES THE CERTIFICATE OF DESIGNATIONS IN RESPECT OF THE SERIES A PREFERRED STOCK, AS EXHIBIT A, THE FORM OF RIGHT CERTIFICATE AS EXHIBIT B AND THE SUMMARY OF RIGHTS TO PURCHASE SERIES A PREFERRED STOCK AS EXHIBIT C. PURSUANT TO THE RIGHTS AGREEMENT, RIGHT CERTIFICATES WILL NOT BE MAILED UNTIL AFTER THE SEPARATION DATE (AS DEFINED THEREIN).(4) 4.5 AMENDMENT, DATED AS OF APRIL 24, 1995, TO RIGHTS AGREEMENT, DATED AS OF DECEMBER 15, 1994, BETWEEN ARIAD PHARMACEUTICALS, INC. AND STATE STREET BANK AND TRUST COMPANY.(6) 4.6 STOCK PURCHASE AGREEMENT, DATED AS OF APRIL 24, 1995, BETWEEN ARIAD PHARMACEUTICALS, INC. AND BIOTECH TARGET S.A.(7) 10.1 LEASE AGREEMENT, DATED JANUARY 8, 1992, BETWEEN ARIAD PHARMACEUTICALS, INC. AND FOREST CITY CAMBRIDGE, INC.(1) 10.2 EXECUTIVE EMPLOYMENT AGREEMENT, DATED AS OF JANUARY 1, 1992, BETWEEN ARIAD PHARMACEUTICALS, INC. AND HARVEY J. BERGER, M.D.(1) 10.3 EXECUTIVE EMPLOYMENT AGREEMENT, DATED AS OF JANUARY 3, 1992, BETWEEN ARIAD PHARMACEUTICALS, INC. AND JOAN S. BRUGGE, PH.D.(1) 10.4 EXECUTIVE EMPLOYMENT AGREEMENT, DATED AS OF JANUARY 1, 1992, BETWEEN ARIAD PHARMACEUTICALS, INC. AND CHARLES C. CABOT III.(1) 10.5 EXECUTIVE EMPLOYMENT AGREEMENT, DATED AS OF JANUARY 1, 1992, BETWEEN ARIAD PHARMACEUTICALS, INC. AND JAY R. LAMARCHE.(1) 10.6 EXECUTIVE EMPLOYMENT AGREEMENT, DATED AS OF OCTOBER 14, 1991, BETWEEN ARIAD PHARMACEUTICALS, INC. AND MANFRED WEIGELE, PH.D.(1) 10.7 LOAN AND SECURITY AGREEMENT, DATED SEPTEMBER 23, 1992, BY AND BETWEEN ARIAD PHARMACEUTICALS, INC., ARIAD CORPORATION AND BAYBANK BOSTON, N.A. AND RELATED INSTRUMENTS AND DOCUMENTS.(1) 10.8 LOAN AGREEMENT, DATED OCTOBER 28, 1992, AMONG ARIAD CORPORATION, ARIAD PHARMACEUTICALS, INC. AND THE MASSACHUSETTS BUSINESS DEVELOPMENT CORPORATION AND RELATED INSTRUMENTS AND DOCUMENTS.(1) 10.9 EQUIPMENT LEASE AGREEMENT, DATED DECEMBER 10, 1992, BY AND BETWEEN ARIAD CORPORATION AND GENERAL ELECTRIC CAPITAL CORPORATION.(1) 10.10 MASTER LEASE AGREEMENT, DATED DECEMBER 21, 1992, BY AND BETWEEN ARIAD CORPORATION AND COMDISCO, INC.(1) 10.11 ARIAD PHARMACEUTICALS, INC. 1991 STOCK OPTION PLAN FOR EMPLOYEES, AS AMENDED.(5) 10.12 ARIAD PHARMACEUTICALS, INC. 1991 STOCK OPTION PLAN FOR DIRECTORS.(1) 10.13 ARIAD RETIREMENT SAVINGS PLAN.(1) 10.14 AMENDED AND RESTATED AGREEMENT DATED AS OF DECEMBER 12, 1997 BETWEEN THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY AND ARIAD GENE THERAPEUTICS, INC.(9) 10.15 AMENDMENT, DATED APRIL 19, 1994, TO EXECUTIVE EMPLOYMENT AGREEMENT BETWEEN ARIAD PHARMACEUTICALS, INC. AND HARVEY J. BERGER, M.D.(3) 13 16 10.16 AMENDMENT, DATED MARCH 2, 1994, TO EXECUTIVE EMPLOYMENT AGREEMENT BETWEEN ARIAD PHARMACEUTICALS, INC. AND JOAN S. BRUGGE, PH.D.(3) 10.17 AMENDMENT, DATED MARCH 2, 1994, TO EXECUTIVE EMPLOYMENT AGREEMENT BETWEEN ARIAD PHARMACEUTICALS, INC. AND CHARLES C. CABOT III.(3) 10.18 AMENDMENT, DATED MARCH 2, 1994, TO EXECUTIVE EMPLOYMENT AGREEMENT BETWEEN ARIAD PHARMACEUTICALS, INC. AND JAY R. LAMARCHE.(3) 10.19 AMENDMENT, DATED MARCH 2, 1994, TO EXECUTIVE EMPLOYMENT AGREEMENT BETWEEN ARIAD PHARMACEUTICALS, INC. AND MANFRED WEIGELE, PH.D.(3) 10.20 UNIT PURCHASE AND TECHNOLOGY RIGHT OF FIRST NEGOTIATION AGREEMENT, DATED MAY 5, 1994, AMONG GENENTECH, INC., ARIAD PHARMACEUTICALS, INC. AND ARIAD GENE THERAPEUTICS, INC.(3) 10.21 AMENDMENT NO. 2, DATED JUNE 30, 1994, TO EXECUTIVE EMPLOYMENT AGREEMENT BETWEEN ARIAD PHARMACEUTICALS, INC. AND HARVEY J. BERGER, M.D.(5) 10.22 ARIAD PHARMACEUTICALS, INC. 1994 STOCK OPTION PLAN FOR NON-EMPLOYEE DIRECTORS.(5) 10.23 COLLABORATIVE RESEARCH AND LICENSE AGREEMENT, DATED NOVEMBER 5, 1995, BETWEEN ROUSSEL UCLAF AND ARIAD PHARMACEUTICALS, INC.(7) 10.24 LICENSE AGREEMENT DATED AS OF SEPTEMBER 12, 1996 BETWEEN MOCHIDA PHARMACEUTICALS CO., LTD. AND ARIAD PHARMACEUTICALS, INC.(8) 10.25 JOINT VENTURE AGREEMENT DATED AS OF FEBRUARY 14, 1997 BETWEEN GENOVO, INC. AND ARIAD GENE THERAPEUTICS, INC.(8) 10.26 JOINT VENTURE MASTER AGREEMENT DATED AS OF MARCH 4, 1997 BETWEEN HOECHST MARION ROUSSEL, INC. AND ARIAD PHARMACEUTICALS, INC.(8) 10.27 STOCK PURCHASE, STANDSTILL AND REGISTRATION RIGHTS AGREEMENT DATED AS OF MARCH 4, 1997 BETWEEN HOECHST MARION ROUSSEL, INC. AND ARIAD PHARMACEUTICALS, INC.(8) 10.28 COLLABORATIVE AGREEMENT DATED AS OF MARCH 4, 1997 BETWEEN INCYTE PHARMACEUTICALS, INC. AND ARIAD PHARMACEUTICALS, INC.(8) 10.29 AMENDMENT, DATED JANUARY 1, 1997, TO EXECUTIVE EMPLOYMENT AGREEMENT BETWEEN ARIAD PHARMACEUTICALS, INC. AND HARVEY J. BERGER, M.D.(8) 10.30 AMENDMENT, DATED JANUARY, 1, 1997, TO EXECUTIVE EMPLOYMENT AGREEMENT BETWEEN ARIAD PHARMACEUTICALS, INC. AND JAY R. LAMARCHE(8) 10.31 AMENDMENT, DATED JANUARY 1, 1997, TO EXECUTIVE EMPLOYMENT AGREEMENT BETWEEN ARIAD PHARMACEUTICALS, INC. AND CHARLES C. CABOT III(8) 10.32 AMENDMENT, DATED JANUARY 1, 1997, TO EXECUTIVE EMPLOYMENT AGREEMENT BETWEEN ARIAD PHARMACEUTICALS, INC. AND MANFRED WEIGELE, PH.D.(8) 10.33 AMENDMENT, DATED JANUARY 1, 1997, TO EXECUTIVE EMPLOYMENT AGREEMENT BETWEEN ARIAD PHARMACEUTICALS, INC. AND MICHAEL GILMAN, PH.D.(8) 10.34 CONSULTING AGREEMENT, DATED JULY 1, 1997, BETWEEN ARIAD PHARMACEUTICALS, INC. AND JOAN S. BRUGGE, PH.D.(8) 10.35 ARIAD PHARMACEUTICALS, INC. 1997 EMPLOYEE STOCK PURCHASE PLAN(8) 10.36 AMENDMENT TO THE 1991 STOCK OPTION PLAN FOR EMPLOYEES AND CONSULTANTS (8) 10.37 AMENDMENT TO THE 1994 STOCK OPTION PLAN FOR NON-EMPLOYEE DIRECTORS(8) 10.38 FOURTH AMENDMENT TO LOAN AND SECURITY AGREEMENT DATED JUNE 27, 1997 WITH BANKBOSTON, N.A. AS SUCCESSOR IN INTEREST TO BAYBANK, N.A.(8) 10.39 LICENSE AGREEMENT, DATED JULY 17, 1997, BETWEEN ARIAD PHARMACEUTICALS, INC. AND MITOTIX INC.(8) 10.40 TECHNOLOGY PURCHASE AND SALE AGREEMENT AND RELATED AGREEMENTS, DATED JULY 17, 1997, BETWEEN ARIAD PHARMACEUTICALS, INC. AND MITOTIX, INC. (8) 10.41 ARIAD PHARMACEUTICALS, INC. 1997 EXECUTIVE COMPENSATION PLAN(9) 21.1 SUBSIDIARIES OF THE COMPANY.(3) 27.1 FINANCIAL DATA SCHEDULE.(10) - ---------- (1) INCORPORATED BY REFERENCE TO REGISTRATION STATEMENT ON FORM 10 OF THE COMPANY FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON JUNE 25, 1993. (2) INCORPORATED BY REFERENCE TO FORM 10-K OF THE COMPANY FOR THE FISCAL YEAR ENDED DECEMBER 31, 1993 FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON APRIL 15, 1994. (3) INCORPORATED BY REFERENCE TO REGISTRATION STATEMENT ON FORM S-1 OF THE COMPANY (NO. 33-76414) FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON MARCH 11, 1994. 14 17 (4) INCORPORATED BY REFERENCE TO FORM 8-K OF THE COMPANY FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON DECEMBER 21, 1994. (5) INCORPORATED BY REFERENCE TO FORM 10-K OF THE COMPANY FOR THE FISCAL YEAR ENDED DECEMBER 31, 1994 FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON MARCH 30, 1995. (6) INCORPORATED BY REFERENCE TO FORM 8-K OF THE COMPANY FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON MAY 15, 1995. (7) INCORPORATED BY REFERENCE TO FORM 10-K OF THE COMPANY FOR THE FISCAL YEAR ENDED DECEMBER 31, 1995 FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON MARCH 15, 1996. (8) INCORPORATED BY REFERENCE TO FORMS 10-Q OF THE COMPANY FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON MAY 12, 1997, AUGUST 12, 1997 AND NOVEMBER 12, 1997. (9) INCORPORATED BY REFERENCE TO FORM 10-K OF THE COMPANY FOR THE FISCAL YEAR ENDED DECEMBER 31, 1997 FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON MARCH 6, 1998. (10) FILED HEREWITH. 15 EX-27 2 FINANCIAL DATA SCHEDULE
5 1 US$ 6-MOS DEC-31-1998 JAN-01-1998 JUN-30-1998 1 8,499,005 13,926,520 0 0 0 25,079,405 17,158,319 7,702,414 41,319,706 11,007,358 4,231,486 0 25,263 21,882 26,033,717 41,319,706 0 6,683,216 0 0 18,101,692 0 258,124 (11,676,600) 0 0 0 0 0 (11,676,600) (.58) (.58)
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