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Significant Accounting Policies (Details)
3 Months Ended 5 Months Ended 9 Months Ended 48 Months Ended
Sep. 30, 2016
USD ($)
customer
shares
Sep. 30, 2015
USD ($)
customer
May 31, 2016
USD ($)
Sep. 30, 2016
USD ($)
customer
segment
shares
Sep. 30, 2015
USD ($)
customer
Dec. 31, 2015
USD ($)
Concentration Risk [Line Items]            
Total of realized and unrealized transaction losses $ 34,000     $ 900,000    
Total of realized and unrealized transaction gains   $ 200,000     $ 800,000  
Marketable securities 9,627,000     9,627,000   $ 11,407,000
Carrying value of equity method investments 0     0    
Accrued rent 3,600,000     3,600,000   5,400,000
Product revenue, net 34,300,000 $ 27,543,000   133,260,000 $ 79,262,000  
Advanced payments from customers 4,532,000     $ 4,532,000   23,545,000
Number of operating segments | segment       1    
Geographic concentration risk            
Concentration Risk [Line Items]            
Long-lived assets $ 0     $ 0   1,400,000
Net product revenue | Customer concentration risk            
Concentration Risk [Line Items]            
Number of customers accounting for more than ten percent of net revenue | customer 2 1   1 1  
Concentration risk, percentage   70.00%   61.00% 74.00%  
Net product revenue | Customer concentration risk | Customer One            
Concentration Risk [Line Items]            
Concentration risk, percentage 73.00%          
Net product revenue | Customer concentration risk | Customer Two            
Concentration Risk [Line Items]            
Concentration risk, percentage 17.00%          
Net product revenue | Geographic concentration risk            
Concentration Risk [Line Items]            
Concentration risk, percentage 27.00% 30.00%   39.00% 26.00%  
Accounts receivable | Customer concentration risk            
Concentration Risk [Line Items]            
Concentration risk, percentage         61.00%  
Number of customers accounting for more than ten percent of accounts receivable | customer       2 1  
Accounts receivable | Customer concentration risk | Customer One            
Concentration Risk [Line Items]            
Concentration risk, percentage       60.00%    
Accounts receivable | Customer concentration risk | Customer Two            
Concentration Risk [Line Items]            
Concentration risk, percentage       39.00%    
FRANCE            
Concentration Risk [Line Items]            
Product revenue, net       $ 25,500,000    
Deferred revenue recognized     $ 3,000,000     22,500,000
Advanced payments from customers $ 4,500,000     $ 4,500,000    
FRANCE | Net product revenue | Geographic concentration risk            
Concentration Risk [Line Items]            
Concentration risk, percentage       17.00%    
Other long-term liabilities            
Concentration Risk [Line Items]            
Accrued rent, noncurrent           4,800,000
Other current liabilities            
Concentration Risk [Line Items]            
Accrued rent, current $ 3,600,000     $ 3,600,000   $ 600,000
REGENXBIO, Inc. | Common Stock            
Concentration Risk [Line Items]            
Marketable securities (in shares) | shares 687,139     687,139    
REGENXBIO, Inc. | Common Stock | Level 1            
Concentration Risk [Line Items]            
Marketable securities $ 9,600,000     $ 9,600,000    
Marketable securities, unrealized gain $ 4,100,000          
Marketable securities, unrealized loss       $ 1,800,000