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Long-term Debt (Details) - USD ($)
$ in Thousands
Jun. 30, 2016
Dec. 31, 2015
Debt Instrument [Line Items]    
Long-Term Debt And Financing Lease Obligations $ 491,279 $ 443,092
Less current portion (24,522) (13,872)
Long term portion 466,757 429,220
Convertible notes, net    
Debt Instrument [Line Items]    
Long-Term Debt And Financing Lease Obligations 168,884 164,438
Royalty financing, net    
Debt Instrument [Line Items]    
Long-Term Debt And Financing Lease Obligations 46,619 46,921
Facility lease obligation    
Debt Instrument [Line Items]    
Long-Term Debt And Financing Lease Obligations $ 275,776 $ 231,733