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Long-term Debt (Details) - USD ($)
$ in Thousands
Mar. 31, 2016
Dec. 31, 2015
Debt Instrument [Line Items]    
Long-Term Debt And Financing Lease Obligations $ 462,155 $ 443,092
Less current portion (16,636) (13,872)
Long term portion 445,519 429,220
Convertible notes, net    
Debt Instrument [Line Items]    
Long-Term Debt And Financing Lease Obligations 166,635 164,438
Royalty financing, net    
Debt Instrument [Line Items]    
Long-Term Debt And Financing Lease Obligations 46,885 46,921
Facility lease obligation    
Debt Instrument [Line Items]    
Long-Term Debt And Financing Lease Obligations $ 248,635 $ 231,733